中国真菌学杂志2025,Vol.20Issue(5):494-497,4.DOI:10.3969/j.issn.1673-3827.2025.05.009
老年侵袭性肺部真菌感染肺泡灌洗液真菌分布及耐药分析
Fungal distribution and resistance in elderly invasive pulmonary fungal infection patients'bronchoalveolar lavage fluid
王康椿 1王楠 1李冉1
作者信息
- 1. 广东省第二中医院检验科,广东省中医药研究开发重点实验室,广州 510095
- 折叠
摘要
Abstract
Objective To investigate fungal distribution and drug resistance of fungi isolated from elderly invasive pulmonary fungal infection(IPFI)patients'bronchoalveolar lavage fluid,thereby providing a guide for clinical management and infection prevention.Methods Retrospective analysis of fungal culture and drug susceptibility data from bronchoalveo-lar lavage fluid samples(from January 2022 to December 2024)was performed.Results There were 155 fungal isolates i-dentified.C.albicans was predominated(47.7%),followed by C.tropicalis(17.4%),Aspergillus spp.(11.0%)and C.glabrata(10.3%).Multidrug-resistantC.auris accounted for 5.8%.Non-auris Candida showed>95.9%suscepti-bility to(AMB)and 5-fluorocytosine.Conclusion C.albicans remains primary pathogen.Susceptibility testing-guided therapy and strengthened infection control are crucial for elderly IPFI patients.关键词
侵袭性肺部真菌感染/肺泡灌洗液/真菌/耐药Key words
invasive pulmonary fungal infection/bronchoalveolar lavage fluid/fungi/resistance引用本文复制引用
王康椿,王楠,李冉..老年侵袭性肺部真菌感染肺泡灌洗液真菌分布及耐药分析[J].中国真菌学杂志,2025,20(5):494-497,4.