中国造纸2025，Vol.44Issue(10)：24-32,9.DOI:10.11980/j.issn.0254-508X.2025.10.003
季铵化细菌纤维素的制备与抗菌性能研究
Preparation and Antibacterial Properties of Quaternized Modified Bacterial Cellulose
摘要
Abstract
In this study,bromination alkyl substitution was achieved by reacting 2-bromoisobutyryl bromide with the hydroxyl groups of the bac-terial cellulose(BC)molecular chain,thereby anchoring bromine active groups onto the BC framework.Subsequently,surface-initiated atom transfer free radical polymerization(SI-ATRP)was employed to graft diallyldimethylammonium chloride(DADMAC)onto the BC surface,yield-ing quaternary ammonium bacterial cellulose(QBC).A systematic investigation was conducted to elucidate the structure,properties,and anti-bacterial mechanism of QBC.The result showed that extending the quaternization grafting reaction time resulted in the progressive grafting of DADMAC onto the BC chain,with the QBC24 sample obtained after 24 h.During this reaction,the surface roughness of QBC24 increased,the crystallinity index decreased significantly from 80.37％to 73.21％,and the surface Zeta potential shifted from-25.4 mV to 25.1 mV.The quaternary ammonium cations in QBC24 effectively disrupted bacterial cell structures,achieving antibacterial rates exceeding 99％against both Escherichia coli and Staphylococcus aureus,thereby demonstrating excellent broad-spectrum antibacterial performance.关键词
细菌纤维素/抗菌性能/自由基聚合Key words
bacterial cellulose/antibacterial performance/free radical polymerization分类
轻工业引用本文复制引用
卢成帅,戎旭辉,秦柯,孟光范,李霞,韩文佳..季铵化细菌纤维素的制备与抗菌性能研究[J].中国造纸,2025,44(10):24-32,9.基金项目
2024年科教产项目(2024ZDZX01) （2024ZDZX01）
济南市"新高校20条"资助项目(20228103) （20228103）
济南市市校融合发展战略工程项目(JNSX2023040) （JNSX2023040）
山东省自然科学基金(ZR2023QB038) （ZR2023QB038）
齐鲁工业大学科教产融合试点工程基础研究培新项(2023PX055) （2023PX055）
山东省科技型中小企业创新能力提升工程项目(2023TSGC0319). （2023TSGC0319）
