中国卒中杂志2025，Vol.20Issue(10)：1222-1228,7.DOI:10.3969/j.issn.1673-5765.2025.10.003
康复脑机接口与运动想象疗法在卒中弛缓性瘫痪期上肢运动功能康复中的疗效对照研究
Comparative Study on the Efficacy of Rehabilitation Brain-Computer Interface versus Motor Imagery Therapy in Upper Limb Motor Function Rehabilitation during the Flaccid Paralysis Phase of Stroke
摘要
Abstract
Objective To compare the clinical efficacy of rehabilitation brain-computer interface(BCI)and motor imagery(MI)therapy on upper limb motor function in stroke patients with the affected hand in the flaccid paralysis phase. Methods Stroke patients with hand dysfunction in the flaccid paralysis phase who were admitted to the Department of Rehabilitation Medicine,The First Affiliated Hospital of Henan Medical University and The Third Affiliated Hospital of Henan Medical University from October 2023 to July 2024,were prospectively and consecutively enrolled and randomly divided into the BCI group and the MI group at a 1∶1 ratio.In addition to conventional rehabilitation training,the BCI group underwent MI-based rehabilitation BCI training,while the MI group received MI training.The training frequency for both groups was six days per week,one session per day,and 30 minutes per session,for two consecutive weeks.Before intervention,one week after intervention,and two weeks after intervention,the Fugl-Meyer motor assessment-upper extremity(FMA-UE)was used to evaluate the patients' upper limb motor function(shoulder/elbow,wrist/hand),the modified Ashworth scale(MAS)was used to assess the muscle tone of patients'upper limb(biceps brachii and triceps brachii),and the modified Barthel index(mBI)was used to evaluate the patients'activities of daily living.Adverse reactions possibly related to rehabilitation BCI device use were recorded.Within-group differences across the assessment time points and between-group differences following the intervention were compared for all outcome measures. Results A total of 37 patients were enrolled,including 18 in the BCI group and 19 in the MI group.After two weeks of intervention,the total FMA-UE score,FMA-UE shoulder/elbow subscore,FMA-UE wrist/hand subscore,and mBI score in both groups were significantly improved compared with those before intervention,with statistically significant differences.After two weeks of intervention,the BCI group demonstrated better outcomes than the MI group in the total FMA-UE score(P=0.006),FMA-UE wrist/hand subscore(P＜0.001),and mBI score(P=0.022),with statistically significant differences.However,no statistically significant difference was found in the FMA-UE shoulder/elbow subscore between the two groups(P=0.057).Regarding MAS grades at one week and two weeks after intervention,there were no statistically significant differences either within each group or between the two groups.No adverse reactions related to the use of the rehabilitation BCI device were reported by any patient. Conclusions Rehabilitation BCI can improve upper limb motor function and effectively enhance the activities of daily living in stroke patients during the flaccid paralysis phase,with good safety.Compared with conventional MI training,rehabilitation BCI training demonstrates superior efficacy in rehabilitating distal upper limb function.关键词
康复脑机接口/运动想象/卒中/上肢运动功能康复Key words
Rehabilitation brain-computer interface/Motor imagery/Stroke/Upper limb motor function rehabilitation分类
临床医学引用本文复制引用
贺新源,王正辉,夏俊博,吴理剑,张海娜,王玉昌,贾杰..康复脑机接口与运动想象疗法在卒中弛缓性瘫痪期上肢运动功能康复中的疗效对照研究[J].中国卒中杂志,2025,20(10):1222-1228,7.基金项目
上海市2024年度"科技创新行动计划"养老科技支撑专项项目(24YL1900200)中国康复医学会科技发展项目(KFKT-2023-049) （24YL1900200）
