中国卒中杂志2025，Vol.20Issue(10)：1229-1236,8.DOI:10.3969/j.issn.1673-5765.2025.10.004
基于运动想象的康复脑机接口联合重复外周磁刺激对卒中后恢复期患者上肢运动功能的疗效研究
Efficacy of Motor Imagery-Based Rehabilitation Brain-Computer Interface Combined with Repetitive Peripheral Magnetic Stimulation on Upper Limb Motor Function in Patients with Convalescent Phase after Stroke
摘要
Abstract
Objective To explore the effect of motor imagery-based rehabilitation brain-computer interface combined with repetitive peripheral magnetic stimulation on upper limb motor function in patients with convalescent phase after stroke. Methods Patients in the convalescent phase after stroke who were hospitalized in the Department of Rehabilitation Medicine,Affiliated Hospital of Chengdu University from May to August 2025 were prospectively and consecutively enrolled.They were randomly divided into the experimental group and the control group.Both groups received 4 weeks of conventional rehabilitation training and repetitive peripheral magnetic stimulation therapy.On this basis,the experimental group received 4 weeks of motor imagery-based rehabilitation brain-computer interface therapy(5 days a week,once a day,30 minutes per session).Upper limb motor function was evaluated by the Fugl-Meyer motor assessment-upper extremity(FMA-UE)before and after the intervention.Surface electromyography signals were collected from the extensor carpi muscles on the affected side,and the root mean square(RMS)and integrated electromyography(iEMG)values were recorded to evaluate the degree of motor unit recruitment. Results A total of 30 patients in the convalescent phase after stroke were included,with 15 cases in both the experimental group and the control group.Before intervention,there were no statistically significant differences between the two groups in the total score of FMA-UE,FMA-UE shoulder/elbow subscore,FMA-UE wrist/hand subscore,RMS value,and iEMG value.After 4 weeks of intervention,the experimental group showed better results than the control group in the total score of FMA-UE[(39.9±7.8)points vs.(30.7±7.8)points,P=0.003],FMA-UE wrist/hand subscore[(14.5±3.5)points vs.(9.3±3.1)points,P＜0.001],RMS value[(47.90±14.94)μV vs.(32.33±7.84)μV,P=0.002],and iEMG value[(82.69±14.32)μV vs.(66.22±10.88)μV,P=0.001],and the differences were statistically significant. Conclusions Motor imagery-based rehabilitation brain-computer interface combined with repetitive peripheral magnetic stimulation can effectively improve upper limb motor function in patients with convalescent phase after stroke,and this protocol has a better effect on improving distal upper limb motor function.关键词
卒中/脑机接口/重复外周磁刺激/上肢运动功能Key words
Stroke/Brain-computer interface/Repetitive peripheral magnetic stimulation/Upper limb motor function分类
临床医学引用本文复制引用
李欣,王东,石诗萌,陈云,何志杰,贾杰..基于运动想象的康复脑机接口联合重复外周磁刺激对卒中后恢复期患者上肢运动功能的疗效研究[J].中国卒中杂志,2025,20(10):1229-1236,8.基金项目
四川省自然科学基金(24NSFSC2856)四川省卫生健康委员会科技项目(24QNMP077)上海市2024年度"科技创新行动计划"养老科技支撑专项项目(24YL1900200) （24NSFSC2856）
