中国畜禽种业2025，Vol.21Issue(10)：7-15,9.
转录组揭示山麻鸭下丘脑应激敏感性的差异表达分析
Transcriptomic Analysis Reveals Differential Gene Expression Related to Stress Sensitivity in the Hypothalamus of the Anas Poecilorhyncha
摘要
Abstract
To investigate the gene expression differences in the hypothalamus of Anas poecilorhyncha with varying stress sensitivity,we used transcriptomic methods to explore the molecular mechanisms of stress response in this species.A psychological stress model was established by inserting an iron hook into the cage to induce a fear response.Twelve ducks were selected based on their behavioral responses:six with the highest active avoidance and six with the lowest active avoidance.Hypothalamic tissues were collected for transcriptome sequencing.A total of 85 differentially expressed genes were identified between the HAA and LAA groups,including GRIN2C and P2RX1,with 60 genes upregulated and 25 downregulated in the HAA group.These genes were primarily enriched in calcium signaling pathway and neuroactive ligand-receptor interaction pathway.These findings suggest that GRIN2C,P2RX1,and other genes in the hypothalamus may modulate the avoidance response of Anas poecilorhyncha by participating in calcium signaling and neuroactive ligand-receptor interaction.关键词
应激/山麻鸭/下丘脑/转录组Key words
Stress/Anas poecilorhyncha/Hypothalamus/Transcriptome分类
农业科技引用本文复制引用
彭颖,顾天天,郭融冰,田勇,陈黎,许文武,曾涛,卢立志..转录组揭示山麻鸭下丘脑应激敏感性的差异表达分析[J].中国畜禽种业,2025,21(10):7-15,9.基金项目
国家自然科学基金(32172688) （32172688）
国家重点研发计划(2022YFF1000800) （2022YFF1000800）
国家现代农业产业技术体系(CARS-42-6). （CARS-42-6）
