中国猪业2025，Vol.20Issue(5)：3-13,11.DOI:10.16174/j.issn.1673-4645.2025.05.005
基于SNP芯片的稻城藏猪保种群体遗传结构分析
Analysis of Genetic Structure of Daocheng Tibetan Pigs Conservation Population Based on SNP Chip
摘要
Abstract
This study aimed to elucidate the genetic structure of Tibetan pig conservation populations,analyze their genetic diversity,and construct molecular pedigrees,thereby providing a theoretical foundation for the scientific conservation and rational utilization of this valuable genetic resource.In this study,111 Daocheng Tibetan pigs(80 boars and 31 sows)were analyzed for genetic diversity and family structure using the"Zhongxin-1 Porcine Breeding Array PLUS chips".The genetic structure analysis results showed that the ef-fective population content(Ne)of the Tibetan pig population was 8.2,the proportion of polymorphic markers(PN)was 0.562,the ob-served heterozygosity(Ho)was 0.219,the expected heterozygosity(He)was 0.215,the polymorphism information content(PIC)was 0.165,and the average inbreeding coefficient calculated based on ROH was 0.09.It indicated that the genetic diversity level of the Ti-betan pig conservation population was relatively low,inbreeding coefficient was relatively high,and a risk of inbreeding within the popu-lation.Existed 80 boars were divided into 17 families,the sows were classified according to their kinship,and 5 sows were distantly re-lated to the boars tested and were classified as"other",maybe it was due to the incomplete original genealogy,and some Tibetan pig lineages with chaotic bloodlines.In summary,the Tibetan pig population had a certain genetic diversity,and there was a risk of inbreed-ing in the population,so in the future,unrelated individuals from other breeding groups can be introduced to enrich the gene pool,and individuals with distant relatives can be preferentially selected for breeding,so as to effectively reduce the level of inbreeding in the group.关键词
藏猪/遗传结构/遗传多样性/分子系谱/SNP/保种Key words
Tibetan pigs/genetic structure/genetic diversity/molecular genealogy/SNP/breed conservation分类
畜牧业引用本文复制引用
沈瑶,呷西彭错,罗淦,格茸卓玛,洛茸拉姆,刘鹏亮,顾以韧..基于SNP芯片的稻城藏猪保种群体遗传结构分析[J].中国猪业,2025,20(5):3-13,11.基金项目
国家自然科学基金项目(32472888) （32472888）
西藏自治区科技计划项目(32472888) （32472888）
四川省科技计划项目(2024YFHZ0373,2021YFYZ0009,2024ZHXC0005) （2024YFHZ0373,2021YFYZ0009,2024ZHXC0005）
四川省生猪创新团队项目(sccxtd-2025-08) （sccxtd-2025-08）
