浙江大学学报（医学版）2025，Vol.54Issue(5)：567-572,6.DOI:10.3724/zdxbyxb-2025-0260
新型抗肿瘤药物超说明书用药管理专家共识
Expert consensus on the management of off-label use of novel antineoplastic agents
摘要
Abstract
To enhance medication safety and rational use,a multidisciplinary expert panel from the Yangtze River Delta region—comprising specialists in pharmacy,clinical medicine,healthcare administration,and evidence-based medicine—was convened to develop this consensus through multiple rounds of Delphi consultation.A management system for the off-label use of novel antineoplastic agents was established,incorporating a tiered management process and a regional information sharing platform.Standardized procedures were implemented to regulate the applications,review,documentation,and dynamic adjustment of off-label use.The regional platform centralizes the collection and evaluation of evidence for off-label usage,facilitating consistent and homogeneous manage-ment across healthcare institutions.The tiered management process and information sharing platform established herein are intended to serve as a practical reference for standardizing the management of off-label use of novel antineoplastic agents in medical institutions.关键词
抗肿瘤药/超说明书用药管理/信息共享平台/专家共识Key words
Antineoplastic agents/Off-label use management/Information sharing platform/Expert consensus分类
医药卫生引用本文复制引用
浙江省医院协会药事管理专业委员会,浙江省医院药事管理质控中心,上海市医院协会临床药事管理专业委员会,江苏省医院协会医院药事管理专业委员会,安徽省医院协会药事管理专业委员会,卢晓阳..新型抗肿瘤药物超说明书用药管理专家共识[J].浙江大学学报（医学版）,2025,54(5):567-572,6.基金项目
国家自然科学基金(81971981) This study was supported by National Natural Science Foundation of China(81971981) （81971981）
