浙江大学学报(医学版)2025,Vol.54Issue(5):583-591,9.DOI:10.3724/zdxbyxb-2025-0413
2024版EAU/ESPU小儿泌尿外科指南有关先天性下尿路梗阻更新要点解读
2024 EAU/ESPU paediatric urology guidelines:key updates on congenital lower urinary tract obstruction and clinical inter-pretation
摘要
Abstract
Congenital lower urinary tract obstruction(CLUTO)is a spectrum of fetal malformations caused by anatomical abnormalities of the urethra,characterized by high rates of perinatal complications and mortality.The 2024 joint guideline from the European Association of Urology(EAU)and the European Society for Paediatric Urology(ESPU)introduced systematic revisions to the comprehensive management of CLUTO.Key updates encompass advancements in prenatal and postnatal screening and precise diagnosis,refined fetal prognosis assessment,clearer indications and modality selection for prenatal intervention,optimization of postnatal treatment strategies,and the establishment of a lifelong follow-up framework within an integrated care pathway.This article elucidates these key updates by comparing the 2024 EAU/ESPU guideline with the 2022 European Rare Kidney Disease Reference Network(ERKNet)consensus.It also discusses ongoing controversies and future research directions.The aim is to provide clinicians with the latest evidence-based insights to inform practice,ultimately improving outcomes and quality of life for children with CLUTO.关键词
先天性下尿路梗阻/后尿道瓣膜/儿童/管理/指南解读Key words
Congenital lower urinary tract obstruction/Posterior urethral valve/Child/Management/Guideline interpretation分类
医药卫生引用本文复制引用
梅伶俐,郑智慧,陶畅,陈光杰,燕翔..2024版EAU/ESPU小儿泌尿外科指南有关先天性下尿路梗阻更新要点解读[J].浙江大学学报(医学版),2025,54(5):583-591,9.基金项目
浙江省医药卫生科技计划(2025KY940) This study was supported by Medical and Healthy Science and Technology Project of Zhejiang Province(2025KY940) (2025KY940)