针灸临床杂志2025，Vol.41Issue(10)：50-56,7.DOI:10.19917/j.cnki.1005-0779.025196
温针灸治疗肠易激综合征肝郁脾虚证的疗效及对胃肠道激素的影响
Efficacy of Needle-Warming Moxibustion in Treating IBS with Liver-Qi Stagnation and Spleen Deficiency and Its Impact on Gastrointestinal Hormones
摘要
Abstract
Objective:To observe the therapeutic effect of needle-warming acupuncture on irritable bowel syndrome(IBS)with Liver-Qi stagnation and Spleen deficiency syndrome and to explore its impact on gastrointestinal hormone levels.Methods:A total of 97 patients with IBS of Liver-Qi stagnation and Spleen deficiency pattern were randomly assigned into the observation group(33 cases,2 dropouts;n=31),the medication group(32 cases,2 dropouts;n=30),and the acupuncture group(32 cases,1 dropout;n=31).The medication group received Tongxiening Granule,three times daily,for 3 weeks.The acupuncture group received body acupuncture at Taichong(LR3),Yinlingquan(SP9),Zusanli(ST36),Shangjuxu(ST37),Tianshu(ST25),Neiguan(PC6),Zhongwan(RN12),and Qihai(RN6);needles were retained for 25 minutes,once every other day,for 3 weeks.The observation group received the same acupuncture protocol as the acupuncture group,with the addition of needle-warming moxibustion at ST25,ST37,and LR3.Before and after the treatment,the following outcomes were assessed:Bristol Stool Form Scale(BSFS)score,IBS Symptom Severity Scale(IBS-SSS),TCM symptom score,gastrointestinal hormone levels(MTL and GAS),IBS Quality of Life(IBS-QOL)score,and psychological status using Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS).At the end of the treatment,safety and clinical efficacy were also evaluated across the three groups.Results:Compared with baseline,all three groups showed significant decreases in the scores of BSFS,IBS-SSS,TCM symptoms,IBS-QOL,SAS,and SDS after the treatment(P＜0.05),whereas serum MTL and GAS levels increased significantly(P＜0.05).Compared with the observation group,both the acupuncture group and the medication group had higher scores of BSFS,IBS-SSS,TCM symptoms,IBS-QOL,SAS,and SDS after the treatment(P＜0.05),whereas the levels of MTL and GAS were lower(P＜0.05).The total effective rate of TCM symptoms was 96.77％(30/31)in the observation group,which was significantly higher than 80.00％(24/30)in the medication group and 83.87％(25/31)in the acupuncture group.The total effective rate of IBS-SSS was 93.55％(29/31)in the observation group,which was significantly higher than 76.67％(23/30)in the medication control group and 74.19％(23/31)in the acupuncture group(P＜0.05).Conclusion:Needle-warming moxibustion demonstrates significant efficacy in the treatment of IBS with Liver-Qi stagnation and Spleen deficiency.It effectively reduces diarrhea and abdominal pain,improves gastrointestinal motility,alleviates anxiety and depression symptoms,and enhances quality of life.Its mechanism may be related to the regulation of gastrointestinal hormone levels.Clinical findings indicate that needle-warming moxibustion is more effective than Tongxiening Granule and conventional acupuncture therapy,with good safety and effectiveness.关键词
肠易激综合征/温针灸/肝郁脾虚/胃肠道激素Key words
Irritable bowel syndrome/Needle-warming moxibustion/Liver-Qi stagnation and Spleen deficiency/Gastrointestinal hormones分类
中医学引用本文复制引用
王敏,曹雨微,张哲,安康,李凯,张照庆,胡飞..温针灸治疗肠易激综合征肝郁脾虚证的疗效及对胃肠道激素的影响[J].针灸临床杂志,2025,41(10):50-56,7.基金项目
武汉市中医药科研重点项目,编号:WZ24M02 （）
武汉市中医药科研项目,编号:WZ20Q06. （）
