中外医学研究2025,Vol.23Issue(29):173-176,4.DOI:10.14033/j.cnki.cfmr.2025.29.048
VE-cadherin在动脉血栓性疾病中的研究进展
Progress in the Study of VE-Cadherin and Arterial Thrombotic Diseases
摘要
Abstract
Vascular endothelial cadherin(VE-cadherin)is a transmembrane glycoprotein specifically expressed by endothelial cells.It combines with various catenins through calcium-dependent adhesion junctions to form a dynamic catenin complex,regulating endothelial barrier homeostasis and signal transduction.Its functional abnormalities are closely related to vascular permeability disorders,inflammatory responses and thrombosis.This paper reviews the latest research progress of VE-cadherin and its application in arterial thrombosis-related diseases,providing new ideas for the early diagnosis,treatment guidance and prognosis judgment of the disease.关键词
血管内皮细胞钙黏蛋白/炎症/血栓Key words
Vascular endothelial cadherin/Inflammation/Thrombus引用本文复制引用
张新月,应琪明,董科迪,吕定丰..VE-cadherin在动脉血栓性疾病中的研究进展[J].中外医学研究,2025,23(29):173-176,4.基金项目
浙江省医药卫生科技项目(2024KY1495) (2024KY1495)
浙江省输血协会绿蔻科研基金资助项目(ZJB-LK-2024-002) (ZJB-LK-2024-002)