中医药信息2025，Vol.42Issue(10)：7-11,5.DOI:10.19656/j.cnki.1002-2406.20251002
基于"肺为血脏"理论探讨气虚血瘀与肺纤维化
Exploring the Relationship between Qi Deficiency and Blood Stasis,and Pulmonary Fibrosis Based on the Theory of"Lung as the Blood Organ"
摘要
Abstract
Pulmonary fibrosis(PF)is a refractory disease in the respiratory system.The theory of"Lung as the Blood Organ"posits that the lung promotes blood generation,produce and circulate blood,and nourishes the body and orifices through its governance over the vessels.As the lung is regarded as the blood organ,it is prone to have blood stasis.This article elucidates the intrinsic connection of Qi deficiency and blood stasis with PF by discussing the theory of"Lung as the Blood Organ"and related evidence of the lung's hematopoietic function in modern medicine.It reveals that Qi deficiency and blood stasis persist throughout the progression of PF,which can be divided into three stages:the initial stage,characterized by lung Qi impairment with emerging blood stasis;the chronic progression stage,marked by Qi-blood deficiency,phlegm-stasis interaction,and collateral obstruction;and the terminal stage,involving deficiency of the lung,spleen and kidney,with Qi-blood insufficiency,and collateral deficiency with stasis.In clinical practice,the core treatment principle should focus on replenishing Qi and activating blood circulation,which can inhibit inflammatory responses,regulate the coagulation system,improve angiogenesis,and delay fibrosis progression,thereby enhancing patients'pulmonary function and quality of life.关键词
肺为血脏/气虚血瘀/肺纤维化/病机/益气活血Key words
Lung as the Blood Organ/Qi deficiency and blood stasis/Pulmonary fibrosis/Pathogenesis/Replenishing qi and activating blood circulation引用本文复制引用
张晓莹,白月洁,王子涵,吕颖玉,孙华茹,朱雪,张心月,邵雨萌..基于"肺为血脏"理论探讨气虚血瘀与肺纤维化[J].中医药信息,2025,42(10):7-11,5.基金项目
国家自然科学基金项目(82104799) （82104799）
