中医药信息2025，Vol.42Issue(10)：73-79,7.DOI:10.19656/j.cnki.1002-2406.20251014
中医药调控血管生成治疗子宫内膜异位症的研究进展
Research Progress on Traditional Chinese Medicine Regulation of Angiogenesis in Endometriosis Treatment
摘要
Abstract
Angiogenesis is a crucial process in the pathological progression of endometriosis(EMs).The dynamic changes in microRNA,exosomes,oxidative stress and hypoxia,hormone metabolism levels,pelvic immunity,and inflammatory microenvironment within ectopic endometrial tissues are closely associated with neovascularization.This article reviews the intervention mechanisms of Traditional Chinese Medicine(TCM)on EMs angiogenesis,providing theoretical basis for exploring the feasibility of anti-angiogenic therapy as targeted treatment for EMs.The study reveals that TCM can regulate the expression and activity of angiogenesis-related factors through multiple targets,thereby intervening in biological behaviors such as adhesion,invasion,and proliferation of ectopic endometrial cells.Consequently,TCM effectively modulates the microenvironment balance of lesions and inhibits excessive vascular growth.关键词
中医药/子宫内膜异位症/血管生成/研究进展Key words
Traditional Chinese medicine/Endometriosis/Angiogenesis/Research progress引用本文复制引用
陈雪君,喻星星,李佩双,彭佳华,丁志玲,梁瑞宁..中医药调控血管生成治疗子宫内膜异位症的研究进展[J].中医药信息,2025,42(10):73-79,7.基金项目
国家自然科学基金项目(82405463,82260948) （82405463,82260948）
中医女性生殖健康及相关疾病研究与转化江西省重点实验室项目(2024SSY06311) （2024SSY06311）
江西省研究生创新专项资金项目(YC2024-S720) （YC2024-S720）
