纺织高校基础科学学报2025，Vol.38Issue(5)：1-8,8.DOI:10.13338/j.issn.1006-8341.2025.05.001
负载姜黄素的醋酸纤维素纳米纤维复合水凝胶的性能及其抗氧化分析
Performance and antioxidant analysis of curcumin-loaded cellulose acetate nanofiber composite hydrogels
摘要
Abstract
To construct a novel hydrogel dressing with both excellent mechanical properties and free radical scavenging capability,a nanofiber-reinforced composite hydrogel(QCS/OD/CA-Cur)was prepared using quaternized chitosan(QCS)and oxidized dextran(OD)as the hydrogel ma-trix,incorporating curcumin-loaded cellulose acetate nanofibers(CA-Cur).The experimental re-sults demonstrate that the introduction of nanofibers significantly enhanced the mechanical prop-erties of the hydrogels.The compressive strength and tensile strength of the nanocomposite hy-drogels were 1.8 times and 2.4 times higher than those of the hydrogel without fibers,respective-ly.Furthermore,significant improvements were observed in swelling behavior,strain capacity,and stability.Free radical scavenging assays revealed that the QCS/OD/CA-Cur hydrogel exhibited outstanding antioxidant performance,achieving a scavenging rate of 60.35％against ABTS cation radicals.The materials used in this hydrogel are natural polymers and their derivatives,which possess good biocompatibility,providing experimental evidence and application potential for the development of biologically friendly antioxidant medical dressings.关键词
姜黄素/季铵化壳聚糖/醋酸纤维素/复合水凝胶/流变/抗氧化Key words
curcumin/quaternized chitosan/cellulose acetate/composite hydrogel/rheology/antioxi-dant分类
轻工业引用本文复制引用
齐伊明,王世新,邓红兵..负载姜黄素的醋酸纤维素纳米纤维复合水凝胶的性能及其抗氧化分析[J].纺织高校基础科学学报,2025,38(5):1-8,8.基金项目
湖北省杰出青年学者自然科学基金(2020CFA105) （2020CFA105）
