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首页|期刊导航|骨研究(英文版)|Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation

Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation

Drishti Maniar M.Cole Keenum Casey E.Vantucci Tyler Guyer Paramita Chatterjee Kelly Leguineche Kaitlyn Cheung Robert E.Guldberg Krishnendu Roy

骨研究(英文版)2025,Vol.13Issue(5):1224-1238,15.
骨研究(英文版)2025,Vol.13Issue(5):1224-1238,15.DOI:10.1038/s41413-025-00444-x

Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation

Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation

Drishti Maniar 1M.Cole Keenum 1Casey E.Vantucci 1Tyler Guyer 2Paramita Chatterjee 3Kelly Leguineche 2Kaitlyn Cheung 1Robert E.Guldberg 2Krishnendu Roy4

作者信息

  • 1. Wallace H.Coulter Department of Biomedical Engineering,Georgia Institute of Technology and Emory University,Atlanta,GA,USA
  • 2. Department of Bioengineering,University of Oregon,Eugene,OR,USA||Knight Campus for Accelerating Scientific Impact,University of Oregon,Eugene,OR,USA
  • 3. Parker H.Petit Institute for Bioengineering and Bioscience,Georgia Institute of Technology,Atlanta,GA,USA||Marcus Center for Therapeutic Cell Characterization and Manufacturing,Georgia Institute of Technology,Atlanta,GA,USA
  • 4. Wallace H.Coulter Department of Biomedical Engineering,Georgia Institute of Technology and Emory University,Atlanta,GA,USA||Parker H.Petit Institute for Bioengineering and Bioscience,Georgia Institute of Technology,Atlanta,GA,USA||Marcus Center for Therapeutic Cell Characterization and Manufacturing,Georgia Institute of Technology,Atlanta,GA,USA||Department of Biomedical Engineering,Vanderbilt University,Nashville,TN,USA||Department of Pathology,Microbiology,and Immunology,Vanderbilt University Medical Center,Nashville,TN,USA||Department of Chemical and Biomolecular Engineering,Vanderbilt University,Nashville,TN,USA
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摘要

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Drishti Maniar,M.Cole Keenum,Casey E.Vantucci,Tyler Guyer,Paramita Chatterjee,Kelly Leguineche,Kaitlyn Cheung,Robert E.Guldberg,Krishnendu Roy..Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation[J].骨研究(英文版),2025,13(5):1224-1238,15.

骨研究(英文版)

2095-4700

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