摘要
Abstract
Objective To evaluate left ventricular function in obese patients using left ventricular pressure-strain loops(LVPSL),measure their epicardial adipose tissue(EAT)thickness,and explore the value of EAT thickness in predicting LV dysfunction in obese patients.Methods A total of 116 obese patients who visited Shanxi Bethune Hospital from December 2021 to August 2023 were selected for echocardiography.According to the median thickness of EAT,obese patients were divided into EAT<4.8 mm group and EAT≥4.8 mm group.The parameters of conventional echocardiography,global longitudinal strain(GLS),and myocardial work(MW)parameters obtained through LVPSL analysis were compared between the two groups,and the correlation between left ventricular MW parameters and EAT was analyzed.Results Compared with the EAT<4.8 mm group,the EAT≥4.8 mm group had a decrease in left ventricular GLS,GCW,GWI,GWE,and an increase in GWW,with statistically significant differences(P<0.05).Pearson correlation analysis showed that GLS,GCW,and GWI were negatively correlated with EAT in obese patients(r=-0.286,-0.313,-0.367,P<0.05),while GWW and GWE were not significantly correlated with EAT(P>0.05).Conclusion Non-invasive LVPSL can early and accurately assess the left ventricular myocardial function of obese patients,which has important clinical value.And the thicker the eat thickness in obese patients,the more serious the left ventricular myocardial function damage.EAT can be regarded as a useful indicator for early identification of impaired left ventricular myocardial function in obese patients.关键词
肥胖/心外膜脂肪/左室压力-应变环/心肌做功/心肌功能Key words
obesity/epicardial fat/left ventricular pressure strain loop/myocardial work/myocardial function