临床肝胆病杂志2025，Vol.41Issue(10)：2125-2129,5.DOI:10.12449/JCH251024
基于伏邪理论探讨干扰素治疗慢性乙型肝炎的疗效特点及中医药协同减毒增效机制
Efficacy of interferon in treatment of chronic hepatitis B and the synergistic mechanism of traditional Chinese medicine in toxicity reduction and efficacy enhancement:A study based on the theory of latent pathogens
摘要
Abstract
In the traditional theoretical system of traditional Chinese medicine,latent pathogenic factors deeply hiding in the liver and gallbladder of the Jueyin meridian are the core pathogenesis of chronic hepatitis B.Interferon can regulate immunity and eliminate viruses,and clinical cure can be achieved by penetrating and removing pathogenic factors and toxins.However,it often causes dizziness and confusion reactions in the initial stage of treatment,and long-term use can damage Qi-blood;furthermore,its therapeutic effect depends on the patient's own vital Qi.When traditional Chinese medicine is used in combination with interferon,drug compatibility should be adjusted according to the dynamic changes of pathogenesis,which can reduce adverse reactions,enhance the therapeutic outcome,expand the applicable population of interferon,and improve the clinical symptoms of patients.关键词
乙型肝炎,慢性/伏邪/干扰素类/中医药疗法Key words
Hepatitis B,Chronic/Latent Pathogens/Interferons/Traditional Chinese Medicine Therapy引用本文复制引用
王石中,郑润锈,孙克伟..基于伏邪理论探讨干扰素治疗慢性乙型肝炎的疗效特点及中医药协同减毒增效机制[J].临床肝胆病杂志,2025,41(10):2125-2129,5.基金项目
国家自然科学基金(8197152432) （8197152432）
2023年湖南中医药大学双一流学科建设项目(6001001007) National Natural Science Foundation of China(8197152432) （6001001007）
Double First-Class Discipline Construction Project of Hunan University of Chinese Medicine in 2023(6001001007) （6001001007）
