临床肝胆病杂志2025，Vol.41Issue(10)：2130-2135,6.DOI:10.12449/JCH251025
巨噬细胞糖酵解在代谢相关脂肪性肝病中的调控作用
Regulatory role of macrophage glycolysis in metabolic dysfunction-associated fatty liver disease
摘要
Abstract
Metabolic dysfunction-associated fatty liver disease(MAFLD)is a common chronic liver disease in clinical practice,and macrophages are directly involved in the development,progression,and prognosis of MAFLD.Studies have confirmed that glucose metabolic reprogramming in macrophages directly affects immune function,which in turn affects the local inflammatory environment of liver and hepatocyte metabolism.This article reviews the changes in glucose metabolism of macrophages and the corresponding key molecules in the pathogenesis of MAFLD,in order to provide new targets and strategies for the prevention and treatment of MAFLD in the future.关键词
代谢相关脂肪性肝病/巨噬细胞/糖酵解/代谢重编程Key words
Metabolic Dysfunction-Associated Fatty Liver Disease/Macrophages/Glycolysis/Metabolic Reprogramming引用本文复制引用
常嘉涵,蔡玉洁,侯艺鑫,韩聚强..巨噬细胞糖酵解在代谢相关脂肪性肝病中的调控作用[J].临床肝胆病杂志,2025,41(10):2130-2135,6.基金项目
国家自然科学基金(81970512) National Natural Science Foundation of China(81970512) （81970512）
