环境与职业医学2025，Vol.42Issue(10)：1155-1161,7.DOI:10.11836/JEOM25170
非适宜温度对急性酒精中毒120急救量的影响:基于无锡市的时间序列研究
Impact of non-optimal temperature on 120 emergency call volume for acute alcohol intoxica-tion:A time-series study in Wuxi City
摘要
Abstract
[Background]Non-optimal temperatures pose significant threats to public health.Analyzing the association between temperature exposure and the number of emergency cases of acute alcohol intoxication can provide evidence for optimizing emergency resource allocation and response strategies. [Objective]To analyze the overall impact and lag effects of non-optimal temperatures on the number of 120 emergency calls for acute alcohol intoxication in Wuxi,and to assess the at-tributable risk,in order to provide empirical evidence for formulating climate-adaptive public health strategies. [Methods]Call records of acute alcohol intoxication from Wuxi's 120 emergency service,concurrent air pollutant data,and meteorological data(including daily mean temperature)were collected from January 1,2014 to De-cember 31,2020.Distributed lag nonlinear modeling was used for time-series analysis,with cross-basis functions to capture the nonlinear relationship and lag effects between temperature and emergency volume.Confounding factors such as long-term trends,humidity,pol-lutants[ultimately including ozone(O3)and fine particulate matter(PM2.5)],day of the week,and holidays were controlled.The maximum lag period was set to 14 days.Single-day lag and cumulative lag effects of extreme temperatures were analyzed,followed by sensitivity analysis.Effects were quantified using relative risk(RR)and 95％confidence intervals(95％CI),and attributable fractions and numbers for different temperature ranges were calculated. [Results]A total of 10705 emergency cases of acute alcohol intoxication were included during the study period,with males accounting for 89.5％and individuals aged 18-50 years accounting for 83.4％.A non-linear"U-shaped"association was observed between daily mean temperature and the number of emergency calls,with an optimal temperature of 13.3℃.The effect of the extreme low temperature(1.88℃)was statistically significant from lag1 to lag3 after exposure(P<0.05),with the maximum effect at lag1(RR=1.063,95％CI:1.002,1.129).The extreme high temperature(32.3℃)showed an immediate effect,with maximum effect at lag0(RR=1.374,95％CI:1.248,1.512).The cumulative effect analysis showed that the risk associated with high temperature was the highest at lag0-3(RR=2.000,95％CI:1.667,2.399),while the risk associated with low temperature was the highest at lag0-14(RR=1.462,95％CI:1.042,2.051).The at-tribution analysis indicated that the mild heat(>24.7-30.8℃)and heat(>30.8-33.5℃)contributed the largest numbers of attributable cases,with 591 cases(95％CI:56,1032)and 190 cases(95％CI:51,309),respectively.The corresponding attributable fractions were 5.81％(95％CI:0.80％,9.94％)and 1.87％(95％CI:0.49％,2.96％),respectively. [Conclusion]Both extreme high and low temperatures significantly increase the number of 120 emergency calls for acute alcohol intoxi-cation in Wuxi.High temperature exhibit an acute effect,while low temperature show a delayed effect.Mild heat have a significant impact on the emergency burden.It is recommended that emergency departments optimize resource allocation according to climatic character-istics and strengthen emergency responses during extreme weather to reduce alcohol-related health burden.关键词
非适宜温度/急性酒精中毒/120急救量/滞后效应/归因风险/极端高温/极端低温Key words
non-optimal temperature/acute alcohol intoxication/number of 120 emergency calls/lag effect/attributable risk/extreme high temperature/extreme low temperature分类
预防医学引用本文复制引用
杨超,张皖君,李修竹,张旭辉,丁新良,周伟杰,陆春城,朱鹏飞..非适宜温度对急性酒精中毒120急救量的影响:基于无锡市的时间序列研究[J].环境与职业医学,2025,42(10):1155-1161,7.基金项目
无锡市"双百"中青年医疗卫生拔尖人才项目(BJ2023100) （BJ2023100）
无锡市医学重点学科建设项目(LCZX2021006) （LCZX2021006）
