环境与职业医学2025，Vol.42Issue(10)：1193-1200,8.DOI:10.11836/JEOM25004
乌鲁木齐市短期环境温度暴露对居民心率变异性的影响:基于小时尺度的纵向面板研究
Impact of short-term ambient temperature exposure on heart rate variability in residents of Urumqi:An hourly-level longitudinal panel study
摘要
Abstract
[Background]While A few studies have suggested associations between ambient temperature and cardiac autonomic function,the relationship between hourly temperature variations and heart rate variability(HRV)remains unclear. [Objective]To examine the acute effects and lag patterns of short-term ambient temperature exposure on HRV at an hourly temporal resolution during cold and warm seasons,and to further characterize the exposure-response relationships. [Methods]We conducted a longitudinal panel study involving 1047 eligible participants who ordered repeated 24 h ambulatory electrocardiogram monitoring at the First Affiliated Hospital of Xinjiang Medical University in Urumqi,Xinjiang Uygur Autonomous Region,China,between March 2020 and March 2022.Twelve HRV parameters were extracted,including standard deviation of all NN intervals(SDNN),standard deviation of the 5 min averages of NN intervals(SDANN),standard deviation of NN intervals index(SDNNIDX),root mean square of successive differences of adjacent NN intervals(rMSSD),triangle index(TI),percent of NN50 in the total number of NN intervals(pNN50),total power(TP),ultralow frequency(ULF),very low frequency(VLF),low frequency(LF),high frequency(HF),and ratio of low frequency to high frequency(LF/HF).Hourly meteorological data(mean temperature and relative humidity)were obtained from the nearest monitoring stations to participants'residences.Linear mixed effects models(LME)and gener-alized additive mixed effects models(GAMM)were employed to assess temperature-HRV associations and lag patterns during cold(from October to March next year)and warm(from April to September)seasons,with stratification by sex and age. [Results]A total of 1047 Urumqi residents who had repeated 24 h ambulatory electrocardiograms were included in this study.In both cold and warm seasons,the exposure-response relationship between ambient temperature and HRV showed an approximately linear negative correlation with no threshold effect;HRV parameters decreased as ambient temperature increased.The correlation between ambient temperature and HRV usually began at a lag of 6 h and disappeared around 24 h lag.The cold season induced a stronger effect on HRV decline,and for every 1 ℃ increase in ambient temperature during the cold season from lag 0 to 6 h,SDNN decreased by 0.72%,SDNNIDX decreased by 1.46%,TI decreased by 0.07%,SDANN decreased by 1.23%,rMSSD decreased by 1.00%,pNN50 decreased by 2.74%,TP decreased by 3.30%,ULF decreased by 3.74%,VLF decreased by 3.76%,LF decreased by 2.75%,HF decreased by 2.49%,and LF/HF decreased by 0.74%;for every 1 ℃ increase in ambient temperature during the warm season,SDNN decreased by 0.56%,SDNNIDX decreased by 1.08%,TI decreased by 0.29%,SDANN decreased by 0.56%,rMSSD decreased by 0.68%,pNN50 decreased by 2.11%,TP de-creased by 2.64%,ULF decreased by 3.14%,VLF decreased by 2.74%,LF decreased by 1.85%,HF decreased by 1.68%,and LF/HF decreased by 0.47%. [Conclusion]Elevated ambient temperatures in Urumqi are significantly associated with decreased HRV in the residents,affecting cardiac autonomic function.关键词
环境温度/动态心电图/心率变异性/线性混合效应模型/乌鲁木齐市/心血管健康Key words
ambient temperature/ambulatory electrocardiogram/heart rate variability/linear mixed effects model/Urumqi City/cardio-vascular health分类
预防医学引用本文复制引用
邱兴怡,薛晓薇,李文舒,程萌媛,胡嘉禄,陈仁杰..乌鲁木齐市短期环境温度暴露对居民心率变异性的影响:基于小时尺度的纵向面板研究[J].环境与职业医学,2025,42(10):1193-1200,8.基金项目
国家自然科学基金项目(82373532) （82373532）
