上海针灸杂志2025，Vol.44Issue(11)：1353-1359,7.DOI:10.13460/j.issn.1005-0957.2025.11.1353
CT定位下针刺曲骨穴不同深度治疗良性前列腺增生的有效性与安全性评价
Evaluation of the efficacy and safety of acupuncture at different depths at Qugu(CV2)under CT guidance for benign prostatic hyperplasia
摘要
Abstract
Objective To evaluate the efficacy and safety of acupuncture at different depths at Qugu(CV2)under CT guidance in the treatment of benign prostatic hyperplasia(BPH).Method A total of 120 patients with BPH were randomly assigned to three group,CT group 1(n=40,3 dropouts),CT group 2(n=40,6 dropouts),and sham acupuncture group(n=40,7 dropouts).In CT group 1,needles were inserted at Qugu point directly to the prostate capsule;in CT group 2,needles were inserted to approximately 10 mm away from the prostate capsule;in the sham acupuncture group,blunt-tip needle was used at Qugu without penetrating the skin.International prostate symptom score(IPSS),quality of life(QOL)scores,maximum urinary flow rate(Qmax),postvoid residual urine volume(PVR),and prostate volume(PV)were compared among the three groups before and after treatment,as well as at follow-up.Safety evaluation was also performed.Result After treatment,CT Group 1 and CT Group 2 showed significant improvements in IPSS score,QOL score,and Qmax compared to baseline(P＜0.05).There were no statistically significant differences in IPSS score,QOL score and Qmax between before and after treatment in the sham acupuncture group(P＞0.05).There were statistically significant differences in IPSS score,QOL score and Qmax among the three groups after treatment(P＜0.05).The scores in the CT group 1 were better than those in the CT group 2 and the sham acupuncture group(P＜0.05),and those in the CT group 2 were better than those in the sham acupuncture group(P＜0.05).The IPSS scores and QOL scores of the CT Group 1 and CT Group 2 at follow-up were lower than those before treatment(P＜0.05).There was no significant difference in IPSS and QOL scores at follow-up and after treatment in the three groups(P＞0.05).There were significant differences in the IPSS score and QOL score among the three groups at follow-up(P＜0.05),and the scores in the CT group 1 were better than those in the CT group 2 and the sham acupuncture group(P＜0.05),and those in the CT group 2 were better than those in the sham acupuncture group(P＜0.05).There were no statistically significant differences in PVR and PV before and after treatment in the three groups(P＞0.05).No significant differences were observed between CT Group 1 and CT Group 2 in terms of needle tolerance and acupuncture-related discomfort scores(P＞0.05).Conclusion Acupuncture at Qugu reaching the prostate capsule under CT guidance demonstrated superior efficacy compared to needling approximately 10 mm away from the prostate capsule.The therapeutic effect cannot be attributed to a placebo response,remains sustained at 8-week follow-up,and is both safe and effective,although no significant improvement was observed in PVR or PV.关键词
针刺疗法/穴,曲骨/前列腺增生/CTKey words
Acupuncture therapy/Point,Qugu/Prostatic hyperplasia/CT分类
中医学引用本文复制引用
陆永辉,高瞻,陆芳,任华,付建华,孟玉莲,汤翰,李宝赢,吕璞,国文豪,宋辛子..CT定位下针刺曲骨穴不同深度治疗良性前列腺增生的有效性与安全性评价[J].上海针灸杂志,2025,44(11):1353-1359,7.基金项目
北京市科学技术委员会"首都临床诊疗技术研究及示范应用项目"(Z191100006619055) （Z191100006619055）
中国中医科学院科技创新工程"重大攻关项目"基金项目(CI2021A03514) （CI2021A03514）
中国中医科学院科技创新工程创新团队"针灸临床疗效评价创新团队"基金项目(CI2021B012) （CI2021B012）
