首页|期刊导航|食品科学与人类健康（英文）|Glucocorticoid-insulin like growth factor 1 axis programming might be involved in pancreatic β-cell dysplasia and dysfunction in female offspring rats exposed to caffeine prenatally

Glucocorticoid-insulin like growth factor 1 axis programming might be involved in pancreatic β-cell dysplasia and dysfunction in female offspring rats exposed to caffeine prenatally

Shuxia Gui Xiaoling Guo Yongguo Dai Hao Kou Hui Wang

食品科学与人类健康（英文）2025，Vol.14Issue(10)：4262-4277,16.

食品科学与人类健康（英文）2025，Vol.14Issue(10)：4262-4277,16.DOI:10.26599/FSHW.2025.9250711

Glucocorticoid-insulin like growth factor 1 axis programming might be involved in pancreatic β-cell dysplasia and dysfunction in female offspring rats exposed to caffeine prenatally

Shuxia Gui ¹Xiaoling Guo ¹Yongguo Dai ¹Hao Kou ²Hui Wang³

作者信息

1. Department of Pharmacology,School of Basic Medical Sciences,Wuhan University,Wuhan 430071,China
2. Department of Pharmacy,Zhongnan Hospital of Wuhan University,Wuhan 430071,China||Hubei Provincial Key Laboratory of Developmentally Originated Disease,Wuhan 430071,China
3. Department of Pharmacology,School of Basic Medical Sciences,Wuhan University,Wuhan 430071,China||Hubei Provincial Key Laboratory of Developmentally Originated Disease,Wuhan 430071,China
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摘要

关键词

Prenatal caffeine exposure/Pancreatic development/Glucocorticoids/Insulin-like growth factor 1/Intrauterine programming

Key words

Prenatal caffeine exposure/Pancreatic development/Glucocorticoids/Insulin-like growth factor 1/Intrauterine programming

引用本文复制引用

Shuxia Gui,Xiaoling Guo,Yongguo Dai,Hao Kou,Hui Wang..Glucocorticoid-insulin like growth factor 1 axis programming might be involved in pancreatic β-cell dysplasia and dysfunction in female offspring rats exposed to caffeine prenatally[J].食品科学与人类健康（英文）,2025,14(10):4262-4277,16.

基金项目

This work was supported by grants from the National Key Research and Development Program of China(2020YFA0803900),the National Natural Science Foundation of China(U23A20407,82414020,81703631),the Hubei Provincial Natural Science Foundation of China(2024AFB742).Graphical abstract was created with BioRender(https://www.biorender.com/). （2020YFA0803900）

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