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Effect of cholesterol on distribution,cell uptake,and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury

Lingyan Li Ying Chen Xiangchun Shen Ling Tao Xingjie Wu Qianqian Guo Yu'e Wang Zhiyong He Guangqiong Zhang Shaobo Liu Liping Shu Babu Gajendran

药物分析学报（英文）2025，Vol.15Issue(7)：1542-1564,23.

药物分析学报（英文）2025，Vol.15Issue(7)：1542-1564,23.DOI:10.1016/j.jpha.2024.101182

Effect of cholesterol on distribution,cell uptake,and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury

Lingyan Li ¹Ying Chen ¹Xiangchun Shen ¹Ling Tao ¹Xingjie Wu ¹Qianqian Guo ¹Yu'e Wang ¹Zhiyong He ¹Guangqiong Zhang ¹Shaobo Liu ¹Liping Shu ²Babu Gajendran³

作者信息

1. State Key Laboratory of Functions and Applications of Medicinal Plants,School of Pharmaceutical Sciences,Guizhou Medical University,Guiyang,561113,China||The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and The High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability,School of Pharmaceutical Sciences,Guizhou Medical University,Guiyang,561113,China||Key Laboratory of Optimal Utilization of Natural Medicine Resources(The Union Key Laboratory of Guiyang City-Guizhou Medical University),School of Pharmaceutical Sciences,Guizhou Medical University,Guiyang,561113,China
2. School of Basic Medicine,Guizhou Medical University,Guiyang,561113,China
3. State Key Laboratory of Functions and Applications of Medicinal Plants,School of Pharmaceutical Sciences,Guizhou Medical University,Guiyang,561113,China||The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and The High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability,School of Pharmaceutical Sciences,Guizhou Medical University,Guiyang,561113,China
折叠

摘要

关键词

Biological effects/Cellular kinetics/Cholesterol/Inflammation/Network pharmacology/Proteomics

Key words

Biological effects/Cellular kinetics/Cholesterol/Inflammation/Network pharmacology/Proteomics

引用本文复制引用

Lingyan Li,Ying Chen,Xiangchun Shen,Ling Tao,Xingjie Wu,Qianqian Guo,Yu'e Wang,Zhiyong He,Guangqiong Zhang,Shaobo Liu,Liping Shu,Babu Gajendran..Effect of cholesterol on distribution,cell uptake,and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury[J].药物分析学报（英文）,2025,15(7):1542-1564,23.

基金项目

This study was supported by the National Natural Science Foundation of China(Grant Nos.:82260827 and U1812403-4-4),the Guizhou Provincial Science and Technology Projects,China(Grant Nos.:[2020]1Z069,ZK[2022]380,and ZK[2023]303),the Cultivation Project of National Natural Science Foundation of Guizhou Medical University,China(Grant No.:20NSP050),the Guizhou Provincial Scientific and Technologic Innovation Base,China(Grant No.:[2023]003),the High-level Innovation Talents of Guizhou Province,China(Grant No.:GCC[2023]048),and the Startup Fund for High-Level Talent Research at Guizhou Medical University,China(Grant No.:26242020107).We thank the National Joint Local Engineering Laboratory of Guizhou Medical University for cell engineering and biomedicine techniques as well as Guizhou Province Key Laboratory of Regenerative Medicine of Guizhou Medical University and Key Laboratory of Adult Stem Cell Trans-lational Research of Chinese Academy of Medical Sciences for providing the support of the zebrafish experiment platform.Fig.1 and Graphical abstract were drawn by using Figdraw(https://www.figdraw.com). （Grant Nos.:82260827 and U1812403-4-4）

药物分析学报（英文）

ISSN：2095-1779

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