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E3 ubiquitin ligase FBXW11-mediated downregulation of S100A11 promotes sensitivity to PARP inhibitor in ovarian cancer

Ligang Chen Biliang Chen Yi Ru Xiaohui Lv Mingyi Wang Yunge Gao Yanhong Lv Lianghao Zhai Jian Dong Yan Chen Xia Li Xin Guo

药物分析学报（英文）2025，Vol.15Issue(7)：1652-1666,15.

药物分析学报（英文）2025，Vol.15Issue(7)：1652-1666,15.DOI:10.1016/j.jpha.2025.101246

E3 ubiquitin ligase FBXW11-mediated downregulation of S100A11 promotes sensitivity to PARP inhibitor in ovarian cancer

Ligang Chen ¹Biliang Chen ²Yi Ru ³Xiaohui Lv ²Mingyi Wang ⁴Yunge Gao ²Yanhong Lv ²Lianghao Zhai ²Jian Dong ²Yan Chen ⁴Xia Li ³Xin Guo⁵

作者信息

1. Department of Gynecology and Obstetrics,Xijing Hospital,Air Force Medical University,Xi'an,710032,China||Department of Gynecology and Obstetrics,The General Hospital of Western Theater Command PLA,Chengdu,610036,China
2. Department of Gynecology and Obstetrics,Xijing Hospital,Air Force Medical University,Xi'an,710032,China
3. Department of Biochemistry and Molecular Biology,Air Force Medical University,Xi'an,710032,China
4. Department of Gynecology and Obstetrics,The General Hospital of Western Theater Command PLA,Chengdu,610036,China
5. Department of Endoscopic Surgery,Chinese People's Liberation Army 986th Hospital,Air Force Medical University,Xi'an,710054,China
折叠

摘要

关键词

FBXW11/S100A11/PARPi resistance/Ovarian cancer

Key words

FBXW11/S100A11/PARPi resistance/Ovarian cancer

引用本文复制引用

Ligang Chen,Biliang Chen,Yi Ru,Xiaohui Lv,Mingyi Wang,Yunge Gao,Yanhong Lv,Lianghao Zhai,Jian Dong,Yan Chen,Xia Li,Xin Guo..E3 ubiquitin ligase FBXW11-mediated downregulation of S100A11 promotes sensitivity to PARP inhibitor in ovarian cancer[J].药物分析学报（英文）,2025,15(7):1652-1666,15.

基金项目

The present study was supported by the National Natural Sci-ence Foundation of China(Grant Nos.:81972440 and 82002740)and the Natural Science Foundation of Shaanxi Province,China(Grant No.:2024JC-ZDXM-52). （Grant Nos.:81972440 and 82002740）

药物分析学报（英文）

ISSN：2095-1779

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