针刺研究2025，Vol.50Issue(11)：1317-1324,8.DOI:10.13702/j.1000-0607.20241055
穴位贴敷治疗脾虚湿阻型腹泻型肠易激综合征:随机对照试验
Acupoint application therapy for diarrhea-predominant irritable bowel syndrome with spleen deficiency and dampness retention:a randomized controlled trial
摘要
Abstract
Objective To observe the clinical efficacy of acupoint application in the treatment of diarrhea type irritable bowel syndrome(IBS-D)with spleen deficiency and dampness retention.Methods 88 patients with spleen deficiency and dampness retention type IBS-D were randomly divided into a control group(44 cases,1 case dropped out,1 exclusion)and an experimental group(44 cases,2 cases dropped out).The control group was given Bifidobacterium triple active bacteria capsules(Bifico)orally,0.48 g each time,twice a day.Patients in the experimental group applied joint acupoint plaster to Shenque(CV8)in addition to the control group for 12 h each time,once a day.Both groups underwent treatment for 7 d per course,totaling 4 courses.The traditional Chinese medicine syndrome score,IBS severity scale(IBS-SSS)score,and IBS stool characteristics questionnaire(IBS-DSQ)score of the 2 groups were recorded before and after 4 weeks of treatment,and the clinical efficacy of the 2 groups were observed.Results After treatment,the TCM syndrome score,IBS-SSS score,and IBS-DSQ score of both groups of patients was decreased compared to those before treatment(P<0.001),and the experimental group was significantly better than the control group(P<0.01,P<0.001,P<0.05);the symptom scores of diarrhea,abdominal pain,and abdominal fullness in the experimental group were significantly lower than those in the control group(P<0.01,P<0.05),while there were no statistically significant difference in the scores of fatigue and drowsiness,and anorexia between the two groups.The total effective rate of the experimental group was 88.1%(37/42),which was higher than the control group's 73.8%(31/42),and the difference was statistically significant(P<0.05).Conclusion Acupoint application at CV8 can effectively improve diarrhea,abdominal pain,abdominal distension,and stool characteristics in patients with spleen deficiency and dampness retention type IBS-D,and improve their quality of life.The efficacy is definite,safe,and reliable,and it is worthy of further clinical promotion and application.关键词
穴位贴敷/腹泻型肠易激综合征/随机对照试验Key words
Acupoint application/Diarrhea-predominant irritable bowel syndrome/Randomized controlled trial引用本文复制引用
梅笑,王伟,李晓菲,潘海迪,邓华亮..穴位贴敷治疗脾虚湿阻型腹泻型肠易激综合征:随机对照试验[J].针刺研究,2025,50(11):1317-1324,8.基金项目
国家中医药管理局科技司共建科技项目(No.GZY-KJS-SD-2023-035) （No.GZY-KJS-SD-2023-035）
山东省中医药疗效机理重点实验室项目 （）
山东省中医药重点学科中医脾胃病学项目(No.鲁卫中医药科教字[2022]4号) （No.鲁卫中医药科教字[2022]4号）
山东省中医药科技项目(No.面上项目M-2023167) （No.面上项目M-2023167）
