中国水稻科学2025，Vol.39Issue(6)：744-750,7.DOI:10.16819/j.1001-7216.2025.250316
水稻泛素结合酶E2的生物学功能研究进展
Research Progress on Biological Functions of Ubiquitin-conjugating Enzymes in Rice
摘要
Abstract
Ubiquitination is a critical post-translational modification,accounting for 80%-85%of protein degradation in eukaryotes.It regulates protein activity,localization,and function,thereby playing extensive roles in modulating diverse biological processes.The ubiquitin-conjugating enzyme E2,the second key enzyme in the ubiquitination cascade,acts not only as a ubiquitin carrier but also determines the type of ubiquitin linkages and the length of ubiquitin chains.A total of 48 E2 genes have been identified in rice,all encoding proteins that contain a highly conserved UBC(ubiquitin-conjugating)domain.This domain binds to ubiquitin via a thioester bond and forms a specific interaction interface with ubiquitin ligase E3,ensuring the precision of ubiquitin transfer.Studies have shown that E2 enzymes are widely involved in regulating rice growth and development,as well as responses to biotic stresses such as pathogen infection and abiotic stresses including drought and cold.关键词
泛素结合酶/泛素化/蛋白修饰/水稻Key words
ubiquitin-conjugating enzyme/ubiquitination/protein modification/rice引用本文复制引用
王娟,吴丽娟,洪海波,姚志文,王磊,鄂志国..水稻泛素结合酶E2的生物学功能研究进展[J].中国水稻科学,2025,39(6):744-750,7.基金项目
中央级公益性科研院所基本科研业务费专项(CPSIBRF-CNRRI-202305) （CPSIBRF-CNRRI-202305）
中国农业科学院科技创新工程项目. （）
