中国中药杂志2025，Vol.50Issue(20)：5641-5657,17.DOI:10.19540/j.cnki.cjcmm.20250603.203
生姜与干姜的化学成分、药理作用、处方应用研究进展及其质量标志物预测分析
Research progress on chemical constituents,pharmacological effects,and prescription application of Zingiberis Rhizoma Recens and Zingiberis Rhizoma and prediction of their quality markers
摘要
Abstract
Zingiberis Rhizoma Recens and Zingiberis Rhizoma are the fresh and dried rhizomes,respectively,of Zingiber officinale,a plant of the Zingiberaceae family.Both are traditional Chinese medicine(TCM)with medicinal and dietary applications and are essential drugs for dispelling cold in clinical practice.They are commonly used as assistant and guide drugs in classical TCM formulas.Modern research has shown that Zingiberis Rhizoma Recens and Zingiberis Rhizoma contain various chemical constituents,including volatile oils,gingerols,diphenylheptanes,flavonoids,amino acids,sugars,and organic acids.These components exhibit pharmacological activities including anti-inflammatory and analgesic effects,antiemetic properties,antibacterial activity,antioxidant effects,immune regulation,and improvement of cardiovascular and cerebrovascular functions,and are widely applied in the fields of medicine,healthcare,and food.This paper reviews the historical origins and traditional uses,chemical constituents,pharmacological effects,and differences in prescription applications of Zingiberis Rhizoma Recens and Zingiberis Rhizoma.It also conducts a predictive analysis of their quality markers(Q-markers)from multiple aspects,including the uniqueness of chemical constituents,the correlation between traditional properties and pharmacological effects,the measurability of chemical constituents,and the association with synergistic components,aiming to provide a reference for the quality control and evaluation standards of Zingiberis Rhizoma Recens and Zingiberis Rhizoma.关键词
生姜/干姜/化学成分/药理作用/处方应用/质量标志物Key words
Zingiberis Rhizoma Recens/Zingiberis Rhizoma/chemical constituents/pharmacological effects/prescription applica-tion/quality marker引用本文复制引用
李申澳,余卫东,许寅,汪杰,苏梦,张静,彭灿,左池靖..生姜与干姜的化学成分、药理作用、处方应用研究进展及其质量标志物预测分析[J].中国中药杂志,2025,50(20):5641-5657,17.基金项目
大健康研究院新安医学与中医药现代化研究所专项(2023CXMMTCM006) （2023CXMMTCM006）
安徽省高校杰出青年科研项目(2023AH020035) （2023AH020035）
安徽省自然科学基金杰青项目(2408085J048) （2408085J048）
国家中医药管理局高水平中医药重点学科中药资源学(药用植物学)建设项目(zyyzdxk-2023095) （药用植物学）
安徽省科技攻坚计划项目(202423I10050010) （202423I10050010）
安徽高校协同创新项目(GXXT-2022-075,GXXT-2022-084) （GXXT-2022-075,GXXT-2022-084）
