中医临床研究2025，Vol.17Issue(22)：98-104,7.DOI:10.3969/j.issn.1674-7860.2025.22.012
"神经-内分泌-免疫"网络视角下少泽穴对乳房疾病的干预机制
Intervention mechanism of the Shaoze acupoint on breast disease from the perspective of neuro-endocrine-immune network
摘要
Abstract
Breast diseases in traditional Chinese medicine refer to a general term for various diseases occurring in the breast area,including insufficient lactation,galactorrhea,breast lumps,and breast cancer.As common clinical diseases,their incidence rate is continuously rising,seriously affecting the physical and mental health of women.Although traditional treatment methods such as surgery and medication have certain therapeutic effects,their limitations and adverse reactions have prompted people to explore alternative therapies.As a characteristic therapy of traditional Chinese medicine,acupuncture has significant advantages in the intervention of breast diseases.Among them,the Shaoze acupoint(SI1)on the Hand Taiyang(太阳)Small Intestine Meridian,which is closely related to the physiology and pathology of the breast,has become a frequently selected point in clinical practice,with definite therapeutic effects.However,its modern medical mechanism of action still needs to be further explained.Modern medicine reveals that the nervous,endocrine,and immune systems are mutually regulated through neurotransmitters,hormones,and cytokines,etc.,forming a complete regulatory system network,namely the neuro-endocrine-immune network.The information effect generated by stimulating the Shaoze acupoint is amplified through the neuro-endocrine-immune network in a cascade manner,and is output to the target organ at multiple levels and systems,ameliorating its pathological state and thereby treating breast diseases.This article,based on the understanding of the etiology and pathogenesis of breast diseases in traditional Chinese medicine,takes the neuro-endocrine-immune network as the research framework,systematically integrates clinical practice and experimental research results,and systematically explains the mechanism of acupuncture at the Shaoze acupoint in treating breast diseases from the three dimensions of the nervous,endocrine,and immune systems.It reveals the intervention mechanism and biological pathways of the Shaoze acupoint on breast diseases from a holistic perspective,with the aim of providing reliable theoretical support for the research on the treatment of breast diseases by the Shaoze acupoint.关键词
少泽穴/乳房疾病/神经-内分泌-免疫网络/干预机制/针灸Key words
Shaoze acupoint/Breast disease/Neuro-endocrine-immune network/Intervention mechanism/Acupuncture and moxibustion分类
医药卫生引用本文复制引用
王若诗,陈润廷,黄丽贞.."神经-内分泌-免疫"网络视角下少泽穴对乳房疾病的干预机制[J].中医临床研究,2025,17(22):98-104,7.基金项目
广东省医学科研基金项目(B2025732) （B2025732）
广东药科大学校级课程思政项目(广药大[2021]8号) （广药大[2021]8号）
广东药科大学校级一流本科课程项目(广药大[2021]3号) （广药大[2021]3号）
广东药科大学校级教学案例项目(广药大教[2024]6号) （广药大教[2024]6号）
广东药科大学校级教学改革项目(广药大[2024]139号). （广药大[2024]139号）
