广州医药2025，Vol.56Issue(10)：1338-1345,8.DOI:10.20223/j.cnki.1000-8535.2025.10.003
脓毒症患者发生心肌损伤的高危因素分析
High-risk factors for the development of myocardial injury in patients with sepsis
摘要
Abstract
Sepsis currently remains an important global healthcare issue,and a major threat to world public health and patient safety.Sepsis is a life-threatening organ dysfunction caused by dysregulation of the host response to infection,with extremely high morbidity and mortality,which is a major challenge in clinical critical care medicine.During the progression of sepsis,changes such as inadequate tissue perfusion and haemodynamic instability may occur,leading to impairment of multiple organ functions,while the heart is one of the commonly involved vital target organs,and the varying degree of myocardial damage caused by sepsis is known as"septic cardiomyopathy".The mechanisms of its occurrence and development are complex and diverse,involving circulating myocardial inhibitory factors,myocardial auto-factors,and autonomic dysregulation.In this paper,we review the high-risk factors for myocardial injury in septic patients,providing a reference for clinical treatment and prevention.关键词
脓毒症/脓毒性休克/心肌损伤/高危因素Key words
sepsis/septic shock/septic cardiomyopathy/risk factors引用本文复制引用
董基毅,陆金帅..脓毒症患者发生心肌损伤的高危因素分析[J].广州医药,2025,56(10):1338-1345,8.基金项目
新疆维吾尔自治区自然科学基金(2022D01C117) （2022D01C117）
