广州医药2025，Vol.56Issue(10)：1384-1389,6.DOI:10.20223/j.cnki.1000-8535.2025.10.009
血清降钙素原联合营养指标对肝硬化营养状况评定价值的研究
Value of serum procalcitonin combined with nutritional indicators in assessing the nutritional status of liver cirrhosis
摘要
Abstract
Objective To explore the value of procalcitonin(PCT)combined with nutritional indexes in evaluating the nutritional status of liver cirrhosis.Methods A total of 140 patients with cirrhosis admitted to the Department of Infection of the Affiliated Hospital of Youjiang Medical College for Nationalities from February 2021 to March 2022,they were selected and divided into with and without nutritional risk group according to nutritional risk screening 2002(NRS 2002).The levels of body mass index(BMI),hemoglobin(HGB),prealbumin(PA),albumin(ALB)and retinol binding protein(RBP)in two groups of patients with cirrhosis were compared,and the correlation between them and PCT was analyzed.Results The levels of BMI,HGB,ALB,PA and RBP were lower than those of low nutritional risk group(P＜0.05).The nutritional indices(BMI,HGB,ALB,PA,RBP)were negatively correlated with PCT(P＜0.05).Binary Logistics regression analysis showed that ALB and PCT were risk factors affecting nutritional risk in patients with cirrhosis(P＜0.05).ROC results showed that the area under the curve was 0.984(95%confidence interval:0.964～1.000),sensitivity 98.8%,specificity 93.3%,and Yoden index 0.921 for the combined PCT and ALB indexes predicting malnutrition in cirrhosis.The AUC of ALB and PCT were 0.919 and 0.974,respectively.Conclusions The level of PCT in patients with cirrhosis is closely related to their nutritional status,which has certain value in the evaluation of nutritional status,and combined prediction can effectively improve the evaluation value.关键词
降钙素原/肝硬化/营养状况/评定价值Key words
procalcitonin/liver cirrhosis/nutritional status/assessed value引用本文复制引用
叶婷,罗雪清,黄美金,农照美,黄明凤..血清降钙素原联合营养指标对肝硬化营养状况评定价值的研究[J].广州医药,2025,56(10):1384-1389,6.基金项目
广西壮族自治区卫生健康委员会自筹经费课题(Z20200278) （Z20200278）
