南京中医药大学学报2025，Vol.41Issue(11)：1493-1502,10.DOI:10.14148/j.issn.1672-0482.2025.1493
中药调控坏死性凋亡防治呼吸系统病毒感染性疾病
The Role of Traditional Chinese Medicine in Regulating Necroptosis to Prevent and Treat Respiratory Viral Infectious Diseases
摘要
Abstract
Infectious diseases of the respiratory system are very common in clinical practice,among which pneumonia caused by in-fluenza virus infection is characterized by high morbidity and mortality.Current clinical treatments for respiratory viral infections still face challenges such as drug resistance and poor efficacy.Necroptosis,a form of programmed cell death,is closely associated with the progression of respiratory viral infections.Traditional Chinese medicine modulating necroptosis has demonstrated beneficial therapeu-tic effects in these diseases.This paper introduces the concept and mechanisms of necroptosis,reviews recent research on the relation-ship between necroptosis and respiratory virus infections diseases,and summarizes the therapeutic effects of traditional Chinese medi-cine in regulating necroptosis to intervene in these diseases,aiming to provide insights for the development and clinical application of therapeutic agents for respiratory viral infections.关键词
中药/坏死性凋亡/呼吸系统疾病/病毒感染/细胞死亡/流感病毒/鼻病毒/呼吸道合胞病毒Key words
traditional Chinese medicine/necroptosis/respiratory diseases/viral infection/cell death/influenza virus/rhinovirus/respiratory syncytial virus分类
医药卫生引用本文复制引用
谭丽萍,李亚军,林艳,尹俪洁,王修竹,窦环,侯亚义..中药调控坏死性凋亡防治呼吸系统病毒感染性疾病[J].南京中医药大学学报,2025,41(11):1493-1502,10.基金项目
国家重点研发计划(2023YFC2308200) （2023YFC2308200）
国家自然科学基金重点项目(82230120) （82230120）
