南京中医药大学学报2025，Vol.41Issue(11)：1521-1530,10.DOI:10.14148/j.issn.1672-0482.2025.1521
呼吸道合胞病毒的感染路径及其中药干预研究
Research on the Infection Pathway of Respiratory Syncytial Virus and Its Intervention with Traditional Chinese Medicine
摘要
Abstract
Respiratory syncytial virus(RSV)and the acute respiratory infections it induced have become a global key public health issue.However,the existing antiviral drugs are insufficient and have limitations such as drug resistance,limited applicability,and high toxic side effects,which urgently require the development of new therapeutic methods and drugs.As an important part of traditional medicine,traditional Chinese medicine(TCM)and its compound preparations have rich clinical accumulation and potential advantages in the field of antiviral therapy.Their unique targets and multi-link synergistic effects are highly compatible with the complex patho-genic network of RSV.The article aims to describe the infection pathway and key targets of RSV,summarize the progress and shortcom-ings of existing therapeutic methods,and systematically analyze the regulatory mechanism and drug potential of TCM and its compound preparations on different stages of viral infection,so as to provide reference for improving the prevention and control capabilities and de-veloping new antiviral drugs in China.关键词
呼吸道合胞病毒/靶点/中药/方剂/抗病毒/抗炎Key words
respiratory syncytial virus/targets/traditional Chinese medicine/formula/antiviral/anti-inflammatory分类
医药卫生引用本文复制引用
杨筱悠,刘茜茜,乔宏志..呼吸道合胞病毒的感染路径及其中药干预研究[J].南京中医药大学学报,2025,41(11):1521-1530,10.基金项目
国家重点研发计划(2023YFC2308200) （2023YFC2308200）
中药制药过程控制与智能制造技术全国重点实验室开放基金(NZYSKL240107) （NZYSKL240107）
南京中医药大学标志性人才培育项目(RC202402) （RC202402）
南京中医药大学中药学"引领计划"项目(ZYXYL2024-012) （ZYXYL2024-012）
