器官移植2025，Vol.16Issue(6)：819-832,14.DOI:10.12464/j.issn.1674-7445.2025257
中国重症肝衰竭肝移植围手术期管理临床实践指南
Clinical practice guidelines for perioperative management of liver transplantation in patients with severe hepatic failure in China
摘要
Abstract
Severe liver failure is a clinical syndrome characterized by rapid deterioration of liver function,multi-organ dysfunction and high fatality.Medical treatment has limited efficacy,and liver transplantation is the only effective means to save patients'lives.However,the presence of coagulopathy,immune suppression,infection and dysfunction of multiple organs such as the heart,kidneys,lungs and brain in patients,also significantly increases the risk of death during the perioperative period of liver transplantation,limiting the implementation of liver transplantation for patients with severe liver failure.Based on this,Branch of Organ Transplantation of Chinese Medical Association and Transplant Immunology Committee of Branch of Organ Transplantation Physicians of Chinese Medical Doctor Association have organized experts to summarize the literature and combine clinical experience to write this guideline according to the principles of evidence-based medicine,for reference in the clinical work of physicians related to liver transplantation.关键词
肝衰竭/肝移植/围手术期/肝性脑病/肝肾综合征/心血管并发症/体外膜肺氧合/细菌性感染Key words
Liver failure/Liver transplantation/Perioperative period/Hepatic encephalopathy/Hepatorenal syndrome/Cardiovascular complication/Extracorporeal membrane oxygenation/Bacterial infection分类
医药卫生引用本文复制引用
中华医学会器官移植学分会,吕海金,隋昕,陈森飚,李梓钰,邹云山,中国医师协会器官移植医师分会移植免疫专业委员会,易慧敏,杨扬,刘剑戎,范明明,陆平兰,黎利娟,何玉凤..中国重症肝衰竭肝移植围手术期管理临床实践指南[J].器官移植,2025,16(6):819-832,14.基金项目
国家科技重大专项(2023ZD0502403) （2023ZD0502403）
国家自然科学基金面上项目(82270690) （82270690）
广东省重点专项项目(2023B1111050006) （2023B1111050006）
