生殖医学杂志2025，Vol.34Issue(11)：1513-1518,6.DOI:10.3969/j.issn.1004-3845.2025.11.010
120例抗苗勒管激素水平＞20 ng/ml女性病例的回顾性分析
Retrospective analysis of 120 female cases with anti-Müllerian hormone greater than 20 ng/ml
摘要
Abstract
Objectives:To explore the degree and characteristics of abnormal elevation of anti-Müllerian hormone(AMH)in different diseases,and the clinical significance of AMH as a marker. Methods:The clinical diagnosis data of female cases with AMH＞20 ng/ml tested by the Clinical Laboratory of Peking Union Medical College Hospital in 2024 was retrospectively analyzed,and the differences of AMH levels in different diseases were compared. Results:A total of 120 cases with AMH＞20 ng/ml were included and the diagnosis of these cases was classified into three major categories:polycystic ovary syndrome(PCOS),ovarian granulosa cell tumor,and disorders of sexual development(DSD).The average levels of AMH of patients in three categories were(23.96±4.26)ng/ml,(67.60±61.87)ng/ml and(127.08±70.63)ng/ml,the range values were 20.05-41.00 ng/ml,20.50-254.00 ng/ml and 62.00-230.00 ng/ml,respectively.There was a statistically significant difference in AMH levels among different types of diseases(P＜0.05). Conclusions:AMH,as a tumor marker of granulosa cell tumor,has significantly higher levels in granulosa cell tumor patients than in PCOS patients,while the abnormal elevation of AMH in some DSD patients is a marker of androgen synthesis or dysfunction,not a tumor marker.关键词
抗苗勒管激素/多囊卵巢综合征/颗粒细胞瘤/性发育异常Key words
Anti-Müllerian hormone/Polycystic ovary syndrome/Granulosa cell tumor/Disorders of sexual development分类
医药卫生引用本文复制引用
张嘉慧,程歆琦,邓姗..120例抗苗勒管激素水平＞20 ng/ml女性病例的回顾性分析[J].生殖医学杂志,2025,34(11):1513-1518,6.基金项目
国家临床重点专科建设项目(U114000) （U114000）
