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The antibacterial effect of tellurite is achieved through intracellular acidification and magnesium disruption

Wanli Peng Yali Fu Yanqiu Wang Zixin Deng Daijie Chen Shuangjun Lin Rubing Liang

微生物(英文)2025,Vol.4Issue(4):423-436,14.
微生物(英文)2025,Vol.4Issue(4):423-436,14.DOI:10.1002/mlf2.70028

The antibacterial effect of tellurite is achieved through intracellular acidification and magnesium disruption

The antibacterial effect of tellurite is achieved through intracellular acidification and magnesium disruption

Wanli Peng 1Yali Fu 1Yanqiu Wang 1Zixin Deng 1Daijie Chen 2Shuangjun Lin 3Rubing Liang1

作者信息

  • 1. State Key Laboratory of Microbial Metabolism,Joint International Research Laboratory of Metabolic&Developmental Sciences,School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,Shanghai,China
  • 2. State Key Laboratory of Microbial Metabolism,School of Pharmaceutical Sciences,Shanghai Jiao Tong University,Shanghai,China
  • 3. State Key Laboratory of Microbial Metabolism,Joint International Research Laboratory of Metabolic&Developmental Sciences,School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,Shanghai,China||Frontiers Science Center for Transformative Molecules,Shanghai Jiao Tong University,Shanghai,China
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摘要

关键词

antibacterial mechanism/intracellular acidification/magnesium homeostasis/synergistic effect/tellurite

Key words

antibacterial mechanism/intracellular acidification/magnesium homeostasis/synergistic effect/tellurite

引用本文复制引用

Wanli Peng,Yali Fu,Yanqiu Wang,Zixin Deng,Daijie Chen,Shuangjun Lin,Rubing Liang..The antibacterial effect of tellurite is achieved through intracellular acidification and magnesium disruption[J].微生物(英文),2025,4(4):423-436,14.

基金项目

We thank professors Mancheng Tang and Tingting Huang for their helpful discussion.We thank Jingli Hou,Jiugeng Chen,and Lili Jiang(Instrumental Analysis Centre of Shanghai Jiao Tong University)for their assistance in proteomics and ICP-MS analyses.We thank professors Xianming Shi,Hongyu Ou,Chunlei Shi,Tao Dong(South University of Science and Technology of China),and Qing Liu(University of Shanghai for Science and Technology)for assistance with strains.We thank Professor Ping Zhang from the School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,for the assistance with cell lines and cell culture.We thank Professor Daniel L.Hartl(Harvard University)for constructive sugges-tions.This study was supported by grants from the National Science Foundation of China(32170106 and 32370107),the National Key Research and Development Program of China(2021YFA0909500),and the Natural Science Foundation of Shanghai(19ZR1475500 and 23ZR1431300). (Instrumental Analysis Centre of Shanghai Jiao Tong University)

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