西安交通大学学报（医学版）2025，Vol.46Issue(6)：893-899,7.DOI:10.7652/jdyxb202506001
病因导向的U/P-B-C创新诊疗模式在外科重症救治中的探索
Exploration of the etiology-guided U/P-B-C model for diagnosis and treatment in surgical critical care
摘要
Abstract
Critical care medicine(CCM)is a multifaceted discipline challenged by the inherent heterogeneity and complexity of critical illnesses.Establishing precise,standardized diagnostic and therapeutic systems has emerged as a crucial challenge requiring urgent resolution in this field.Surgical critical care,a pivotal branch of CCM,plays an indispensable role in managing patients with severe trauma,postoperative intra-abdominal infections,solid organ transplantation,and other life-threatening conditions.Evidence-based,etiology-guided therapy serves as the cornerstone of surgical critical care,where accurate identification and timely interventions constitute vital determinants for enhancing patient survival rates and improving prognoses.This article proposes an innovative diagnostic and therapeutic paradigm termed the urgency/physics-biology-chemistry(U/P-B-C)model.Built upon the established principle of urgent(urgency,U)life support in surgical critical care,this model emphasizes a novel conceptual framework centered on etiology-based(physics-biology-chemistry,P-B-C)diagnosis and treatment.Implementing the U/P-B-C innovative diagnostic and therapeutic model in surgical critical care facilitates precise identification of the fundamental pathological mechanisms underlying critical clinical conditions with complex and dynamic clinical environments,enables systematic clarification of clinical reasoning,and ultimately supports evidence-informed decision-making.Its core objectives encompass enhancing surgical intensivists' diagnostic-therapeutic capabilities and ensuring rigorous adherence to the principle of etiology-guided therapy,thereby providing both theoretical foundation and practical guidance for improving the success rate of patient resuscitation and optimizing prognosis in surgical critical care settings.关键词
外科重症/紧急/物理-生物-化学(U/P-B-C)创新诊疗模式/病因学/诊疗思维/个体化治疗Key words
surgical critical care medicine/urgency/physics-biology-chemistry(U/P-B-C)diagnosis and treatment/etiology/medical treatment philosophy/personalized therapy分类
医药卫生引用本文复制引用
番敏,苗润晨,刘司南,张烽平,司茹,刘昌,张靖垚..病因导向的U/P-B-C创新诊疗模式在外科重症救治中的探索[J].西安交通大学学报（医学版）,2025,46(6):893-899,7.基金项目
国家自然科学基金资助项目(No.82472191)Supported by the National Natural Science Foundation of China(No.82472191) （No.82472191）
