西安交通大学学报（医学版）2025，Vol.46Issue(6)：900-909,10.DOI:10.7652/jdyxb202506002
肾移植术后肠道微生物群失调及其对患者预后的影响
Gut microbiota after kidney transplantation and its impact on patient prognosis
摘要
Abstract
In recent years,with the advancement of microbial detection technologies,an increasing number of studies have revealed significant differences in the gut microbiota composition of kidney transplant recipients before and after surgery.These changes in the gut microbiota may influence graft function and the occurrence of post-transplant complications through a variety of factors.This article will review the research progress in the relationship between gut microbiota and kidney transplantation.It focuses on the changes in gut microbiota after kidney transplantation.The role of gut microbiota in immune regulation,drug metabolism,graft function protection,and post-transplant complications is also studied.At the same time,these effects may be of great significance in improving the short-term and long-term prognosis of kidney transplant recipients,thus providing a novel idea for further improving kidney transplant prognosis.关键词
肾移植/免疫抑制剂/同种免疫排斥反应/肠道微生物群/移植后并发症Key words
kidney transplantation/immunosuppressant/alloimmune rejection/gut microbiota/post-transplantation complication分类
临床医学引用本文复制引用
付濮萌,刘亚萍,王梦茹,姚青青,任政宇,李红霞..肾移植术后肠道微生物群失调及其对患者预后的影响[J].西安交通大学学报（医学版）,2025,46(6):900-909,10.基金项目
陕西省科技攻关项目(No.2025SF-YBXM-039):西安交通大学第一附属医院重大新医疗新技术项目(No.XJYFY-2021ZD02)Supported by Shaanxi Provincial Science and Technology Research Project(No.2025SF-YBXM-039)and Major New Medical Technolo-gy Project of The First Affiliated Hospital of Xi'an Jiaotong University(No.XJYFY-2021ZD02) （No.2025SF-YBXM-039）
