西安交通大学学报（医学版）2025，Vol.46Issue(6)：930-936,7.DOI:10.7652/jdyxb202506006
逆向半回收技术治疗颅内急性大血管闭塞
Mechanical thrombectomy using the retrograde semi-retrieval technique in the treatment of acute intracranial large vessel occlusion
摘要
Abstract
Objective To investigate the short-term efficacy of the retrograde semi-retrieval technique(RESET)in the treatment of patients with acute intracranial large vessel occlusion.Methods This retrospective study involved 286 patients with acute intracranial large vessel occlusion who underwent mechanical thrombectomy using RESET at Tianjin Huanhu Hospital from November 2017 to March 2019.The patients were divided into two groups based on the presence or absence of intracranial atherosclerotic stenosis(ICAS):ICAS group(n=186,65％)and non-ICAS group(n=100,35％).Baseline characteristics,procedural outcomes,and 90-day modified Rankin Scale(mRS)scores were compared between the two groups.Results The two groups did not significantly differ in baseline characteristics,including age,gender,past medical history,on-admission National Institutes of Health Stroke Scale(NIHSS)score,and Alberta Stroke Program Early CT(ASPECT)score(all P＞0.05).Successful vascular recanalization was achieved in 272 patients(95.1％),with 209 patients(73.1％)achieving complete recanalization with a single thrombectomy attempt.Rescue therapy was required in 33 patients(11.5％).Two patients in the ICAS group died due to postoperative symptomatic intracranial hemorrhage,and one patient in the non-ICAS group died due to postoperative multiple organ failure.Compared with the non-ICAS group,the ICAS group had a significantly longer puncture-to-recanalization time[141.36(124.11,156.53)min vs.65.17(53.92,83.25)min,P＜0.001]but a significantly smaller number of thrombectomy attempts[1.00(1.00,1.00)vs.1.00(1.00,2.00),P=0.002].However,there were no significant differences between the two groups in terms of final recanalization rate,complete recanalization rate with a single thrombectomy attempt,distal embolism or embolization of new territory,symptomatic intracranial hemorrhage,perioperative death,or 90-day mRS score(all P＞0.05).Conclusion RESET demonstrates satisfactory short-term efficacy in the treatment of acute intracranial large vessel occlusion.The number of thrombectomy attempts required for complete recanalization is significantly lower in the ICAS group than in the non-ICAS group,suggesting that RESET is particularly suitable for patients with ICAS.关键词
颅内大血管闭塞/逆向半回收技术(RESET)/机械取栓/颅内动脉粥样硬化性狭窄(ICAS)Key words
intracranial large vessel occlusion/the retrograde semi-retrieval technique(RESET)/mechanical thrombectomy/intracranial atherosclerotic stenosis(ICAS)分类
医药卫生引用本文复制引用
马振健,徐永波,吴文俊,任贺成,李宏,魏铭..逆向半回收技术治疗颅内急性大血管闭塞[J].西安交通大学学报（医学版）,2025,46(6):930-936,7.基金项目
天津市卫生健康科技项目(No.MS20015) （No.MS20015）
天津市科技计划项目(No.19YFZCSY00260) （No.19YFZCSY00260）
天津市教育委员会基金项目(No.2021KJ223) （No.2021KJ223）
天津医科大学第二医院青年科研基金项目(No.2020ydey19)Supported by the Tianjin Health Science and Technology Project(No.MS20015),Tianjin Science and Technology Planning Project(No.19YFZCSY00260),Tianjin Education Commission Fund Project(No.2021KJ223),and Youth Research Fund Project of the Second Hospital of Tianjin Medical University(No.2020ydey19) （No.2020ydey19）
