现代医药卫生2025，Vol.41Issue(11)：2545-2551,7.DOI:10.3969/j.issn.1009-5519.2025.11.008
青壮年甲状腺超声特征参数与MetS及组分的相关性分析
Correlation analysis of thyroid Ultrasound characteristic Parameters and MetS and their components in Young and Middle-aged adults
摘要
Abstract
Objective To explore the correlation between thyroid ultrasound(including texture and gray-scale characteristic parameters)in young and middle-aged adults and metabolic syndrome(MetS)and its components,and to clarify the quantitative diagnostic value of thyroid ultrasound characteristic parameters in young and middle-aged adults for abnormal MetS and its components.Methods A total of 561 young and middle-aged individuals(aged 19-59 years)who underwent physical examinations at the Physical Examina-tion Center of Chongqing Emergency Medical Center from January 2022 to June 2023 were selected as the re-search subjects.By collecting two-dimensional ultrasound images of the thyroid gland,thyroid hormones,waist circumference,fasting blood glucose,blood pressure,blood lipids,liver function,urinary iodine,and uric acid,Two-dimensional ultrasound images of the thyroid were analyzed using DFY-Ⅱ software to obtain texture fea-tures and gray-scale feature parameters,including Angle second moment,energy,Entropy,contrast,uniformi-ty,average gray-scale,average sound intensity,gray-scale standard deviation,sound intensity standard devia-tion,Skewness,and Kurtosis.Analyze its correlation with MetS and its components.According to the MetS di-agnostic criteria formulated by the Diabetes Society of the Chinese Medical Association(CDS),the research subjects were divided into the MetS group and the non-MetS group,and the differences in thyroid ultrasound characteristic parameters between the two groups were compared.The ROC curve was used to calculate the sensitivity and specificity of thyroid ultrasound characteristic parameters in diagnosing abnormal MS and relat-ed biochemical indicators.Results The results showed that the standard deviation of gray scale and sound in-tensity were positively correlated with TT3,TT4,and TPOAb,and Entropy was also positively correlated with TPOAb(P<0.05).There were a correlation between multiple parameters such as the second moment of Angle,energy,Entropy,standard deviation of gray level,and standard deviation of sound intensity and alanine aminotransferase(ALP).There a correlation between uniformity,average gray level,and average sound inten-sity and uric acid level.There a correlation between Kurtosis and fasting blood glucose(P<0.05).There were statistically significant differences in the gray standard deviation and sound intensity standard deviation be-tween MetS patients and non-MetS patients(P<0.05).The areas under the ROC curves(AUC)of Entropy,gray standard deviation,and sound intensity standard deviation for diagnosing MetS were 0.747,0.749,and 0.749,respectively.Conclusion There is a certain correlation between thyroid ultrasound texture,gray-scale parameters and MetS and their components.Thyroid ultrasound texture and gray-scale parameters can provide certain hints for the diagnosis of MetS and component abnormalities.关键词
青壮年/甲状腺超声/特征参数/代谢综合征/定量分析Key words
Young adults/Thyroid ultrasound/Characteristic parameter/Metabolic syndrome/Quan-titative analysis分类
医药卫生引用本文复制引用
刘娅,杨春江,陈静..青壮年甲状腺超声特征参数与MetS及组分的相关性分析[J].现代医药卫生,2025,41(11):2545-2551,7.基金项目
重庆市科卫联合医学科研青年项目(2025QNXM015) （2025QNXM015）
重庆市体育局一般项目(B202338). （B202338）
