现代医药卫生2025，Vol.41Issue(11)：2565-2568,4.DOI:10.3969/j.issn.1009-5519.2025.11.012
动脉瘤性蛛网膜下腔出血后生物标志物的预后价值研究进展
Research progress on prognostic value of biomarkers after aneurysmal subarachnoid hemorrhage
摘要
Abstract
Aneurysmal subarachnoid hemorrhage(aSAH)is mainly caused by rupture of intracranial aneurysms.Hemorrhage occurs in subarachnoid space.It is an acute neurological disease with high disability and mortality.The brain injury associated with aSAH is caused by a variety of injury mechanisms.Early brain injury(EBI)within 72 hours after onset lays the foundation for subsequent pathophysiological changes and poor prognosis in the brain.Among them,the brain immune inflammatory response involves the interaction of a variety of immune cells and active substances,plays an important role in EBI after aSAH,and is also related to delayed brain injury and long-term prognosis.The systemic inflammatory response after aSAH will affect the prognosis and outcome of patients.This article reviews the role of related biomarkers in the occurrence and development of aSAH,in order to provide new research directions and strategies for the diagnosis and treat-ment of aSAH.关键词
蛛网膜下腔出血/炎症机制/生物标志物/转归Key words
Subarachnoid hemorrhage/Inflammation mechanism/Biomarkers/Outcome分类
临床医学引用本文复制引用
王梅雪,赵明洋,翟健明,崔春英,吴庆建..动脉瘤性蛛网膜下腔出血后生物标志物的预后价值研究进展[J].现代医药卫生,2025,41(11):2565-2568,4.基金项目
山东省自然科学基金面上项目(ZR2021MH133). （ZR2021MH133）
