现代医药卫生2025，Vol.41Issue(11)：2656-2661,6.DOI:10.3969/j.issn.1009-5519.2025.11.029
与半月板形态结构病变相关基因的研究进展
Research progress of genes related to meniscus morphological structure lesions
摘要
Abstract
The pathological changes of meniscus are closely related to the occurrence and development of knee osteoarthritis.Existing studies have found that pathological changes such as meniscus tear or protru-sion,discoid meniscus,and meniscus degeneration may be related to specific genes and their related pathways.However,the treatment for these pathological changes is not ideal in the long-term effect.Therefore,early in-tervention of meniscus lesions from the perspective of gene therapy to prevent the occurrence of knee osteoar-thritis may be a potential treatment strategy.This article summarizes the genes found in recent years related to pathological changes such as meniscus tear,meniscus degeneration,discoid meniscus and their possible mechanisms,aiming to provide intervention strategies for preventing meniscus lesions from progressing to os-teoarthritis.关键词
半月板/半月板病理/膝关节骨关节炎/基因Key words
Meniscus/Meniscus pathology/Knee osteoarthritis/Gene分类
临床医学引用本文复制引用
廖世文,徐大为,黄建荣..与半月板形态结构病变相关基因的研究进展[J].现代医药卫生,2025,41(11):2656-2661,6.基金项目
广东省自然科学基金项目(2017A030313606). （2017A030313606）
