局解手术学杂志2025,Vol.34Issue(11):1011-1015,5.DOI:10.11659/jjssx.01E025001
关节软骨类器官的研究进展
Research progress on articular cartilaginous organoids
摘要
Abstract
Articular cartilage is a crucial tissue structure in humans.With ongoing exploration of joint tissue structure and the emergence of innovative biotechnological organoids,various sources of stem cells can be selected for induction to differentiate into articular cartilaginous organoids based on the articular cartilage tissue structure,which can be applied to the treatment of cartilage defects,drug testing,and precision medicine and biological development.This article presents a review of the research progress concerning articular cartilaginous organoids,in order to provide a reference for clinical practice.关键词
关节软骨/类器官/间充质干细胞/TGF-β/SMAD信号通路/进展Key words
articular cartilage/organoids/mesenchymal stem cells/TGF-β/SMAD signaling pathway/progress分类
特种医学引用本文复制引用
史冲,胡清,阮默,徐永清,王颖娜..关节软骨类器官的研究进展[J].局解手术学杂志,2025,34(11):1011-1015,5.基金项目
国家自然科学基金面上项目(31970515) (31970515)
云南省骨科与运动康复临床医学研究中心项目(202102AA310068) (202102AA310068)