中国康复2025，Vol.40Issue(11)：678-682,5.DOI:10.3870/zgkf.2025.11.007
基于功能成像技术探讨针刺治疗轻度认知障碍机制的研究进展
Research progress in the mechanism of acupuncture treatment for mild cognitive impairment based on functional Ima-ging techniques
摘要
Abstract
Mild cognitive impairment(MCI)is a multifactorial and complex neurodegenerative disorder for which effective pharmacological treatments are currently lacking.In this context,acupuncture has emerged as a promising therapeutic intervention.This review synthesizes evidence from studies utilizing functional magnetic resonance ima-ging(fMRI)and functional near-infrared spectroscopy(fNIRS),indicating that acupuncture can modulate neural ac-tivity in brain regions such as the prefrontal cortex,cingulate cortex,and hippocampus.It further enhances func-tional connectivity within critical brain networks,including the default mode network(DMN),central executive net-work(CEN),and salience network(SN),thereby improving cerebral hemodynamics and cognitive performance.Current research remains predominantly focused on efficacy validation,with mechanistic investigations still insuffi-cient and methodologies relatively limited.Future studies should prioritize the integration of multimodal functional imaging techniques to systematically elucidate the neurobiological mechanisms underlying acupuncture treatment for MCI,thereby providing a more robust scientific foundation for its clinical translation and broader application.关键词
针刺/轻度认知功能障碍/功能成像技术/研究进展Key words
acupuncture/mild cognitive impairment/functional imaging techniques/research progress分类
临床医学引用本文复制引用
王琼瑶,夏文广,种玉飞,龚婧仪,吴青青,黎明..基于功能成像技术探讨针刺治疗轻度认知障碍机制的研究进展[J].中国康复,2025,40(11):678-682,5.基金项目
湖北省中医药管理局项目(ZY2023M016) （ZY2023M016）
湖北省科技厅揭榜制项目(KJJB2023000058) （KJJB2023000058）
湖北省卫生健康委员会项目(WJ2023M101) （WJ2023M101）
