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高级别生物安全实验室非人灵长类解剖操作风险评估与控制措施探究

郑小奇 薛森仁 张贤宇 杨嘉欣 陈渝渝 李小波 林静雯 张亚斌 韩建保

中国比较医学杂志2025,Vol.35Issue(10):69-78,10.
中国比较医学杂志2025,Vol.35Issue(10):69-78,10.DOI:10.3969/j.issn.1671-7856.2025.10.008

高级别生物安全实验室非人灵长类解剖操作风险评估与控制措施探究

Evaluation of non-human primate anatomical operation risk assessment and control measures in high-level biosafety laboratories

郑小奇 1薛森仁 1张贤宇 1杨嘉欣 1陈渝渝 1李小波 1林静雯 1张亚斌 1韩建保1

作者信息

  • 1. 四川大学华西医院高等级生物安全实验室,成都 610041
  • 折叠

摘要

Abstract

Non-human primate animal models are core tools for the study of highly pathogenic microorganisms and are irreplaceable in the fields of pathology and drug discovery.However,anatomical sampling of non-human primate infection models in high-level biosafety laboratories carries potential risk and related risk assessment and control measures require clarification.Based on biosafety regulations and practical experience,we systematically discuss the risk control strategies of anatomical operations with respect to personal protection,instrument selection,anatomical specifications,documentation,and personnel training.Our review will help to improve the management of high-level biosafety laboratories,reduce the risk of pathogen escape and human infection,and provide support for the safe research of highly pathogenic microorganisms.

关键词

高级别生物安全实验室/非人灵长类/动物解剖/风险评估/控制措施

Key words

high-level biosafety laboratory/non-human primate/animal dissection/risk assessment/control measures

分类

医药卫生

引用本文复制引用

郑小奇,薛森仁,张贤宇,杨嘉欣,陈渝渝,李小波,林静雯,张亚斌,韩建保..高级别生物安全实验室非人灵长类解剖操作风险评估与控制措施探究[J].中国比较医学杂志,2025,35(10):69-78,10.

基金项目

四川省科技计划资助(2024NSFSC1749). (2024NSFSC1749)

中国比较医学杂志

OA北大核心

1671-7856

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