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阿尔茨海默病与脑小血管病:交织的病理与共同的征程

赵梦瑶 吕佩源

中国实用内科杂志2025,Vol.45Issue(10):838-842,847,6.
中国实用内科杂志2025,Vol.45Issue(10):838-842,847,6.DOI:10.19538/j.nk2025100107

阿尔茨海默病与脑小血管病:交织的病理与共同的征程

Alzheimer's disease and cerebral small vessel disease:interwoven pathology and common journey

赵梦瑶 1吕佩源2

作者信息

  • 1. 河北省人民医院康复医学科,河北石家庄 050000||河北省脑网络与认知障碍疾病重点实验室,河北石家庄 050000
  • 2. 河北省人民医院神经内科,河北石家庄 050000||河北省脑网络与认知障碍疾病重点实验室,河北石家庄 050000
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摘要

Abstract

Dementia was a global public health issue and has become one of the major chronic diseases seriously threatening human health.Alzheimer's disease(AD)and vascular dementia(VaD)were the two most common causes of dementia in the elderly.Cerebral small vessel disease(CSVD)was a common cause of vascular cognitive impairment.There was a complex interaction between AD and CSVD.This article systematically explores the relationship between the two in terms of clinical phenotypes and pathological mechanisms.It summarizes the current status and challenges in the diagnosis and treatment of AD and emphasizes the significance of managing vascular risk factors in the early intervention of dementia.

关键词

阿尔茨海默病/脑小血管病/病理机制/治疗

Key words

Alzheimer's disease/cerebral small vessel disease/pathological mechanism/treatment

分类

临床医学

引用本文复制引用

赵梦瑶,吕佩源..阿尔茨海默病与脑小血管病:交织的病理与共同的征程[J].中国实用内科杂志,2025,45(10):838-842,847,6.

基金项目

科技创新2030-脑科学与类脑科学重大项目(2021ZD0201807) (2021ZD0201807)

2025年河北省高端人才资助项目(83587216) (83587216)

河北省自然科学基金(H2022307075) (H2022307075)

中国实用内科杂志

OA北大核心

1005-2194

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