中国医学创新2025，Vol.22Issue(31)：141-146,6.DOI:10.3969/j.issn.1674-4985.2025.31.033
金湖地区呼吸道感染人群六种常见呼吸道病原体感染情况及分布特征
Infection Status and Distribution Characteristics of Six Common Respiratory Pathogens in Patients with Respiratory Tract Infections in the Jinhu Region
摘要
Abstract
Objective:To analyze the infection status and distribution characteristics of six common respiratory pathogens among individuals with respiratory tract infections in the Jinhu region.Method:A total of 2,808 patients with respiratory tract infections admitted to Jinhu County People's Hospital from December 2023 to November 2024 were selected as the research subjects.The nucleic acids of influenza A virus,influenza B virus,respiratory syncytial virus,adenovirus,human rhinovirus and Mycoplasma pneumoniae in the throat swab samples of the patients were detected by multiplex real-time fluorescent quantitative PCR technology.The infection status of the six respiratory pathogens and their differences in different genders,ages and seasons were analyzed.Result:The total detection rate of the six respiratory pathogens was 61.15%of the 2,808 samples submitted for testing.Among the 1,707 positive specimens,single infection accounted for 80.55%,double infection and triple infection accounted for 18.11%and 1.34%respectively.The top three detection rates of the six respiratory pathogens were adenovirus(20.16%),human rhinovirus(18.27%),and Mycoplasma pneumoniae(11.11%).There was no statistically significant difference in the detection rates of the six respiratory pathogens between different genders(P>0.05).The detection rates of six respiratory pathogens in different age groups were compared,the differences were statistically significant(P<0.05).Among patients under 18 years old,adenovirus and human rhinovirus detection rates were more high(27.09%and 23.33%),while among patients aged 18 to 35 years old,over 35 to 54 years old and over 54 years old,the detection rate of influenza A virus was the highest(18.45%,17.95%,and 16.17%).The detection rates of the six respiratory pathogens were compared in different seasons,the differences were statistically significant(P<0.05).The highest detection rates in spring and autumn were human rhinovirus(23.93%,21.35%),while in summer and winter,the highest detection rates were adenovirus(26.55%,21.14%).Influenza A virus was more common in autumn and winter,with detection rates of 16.40%and 16.67%,respectively.Influenza B virus was more common in winter and spring,with detection rates of 17.07%and 12.27%,respectively.Respiratory syncytial virus was more common in winter and spring,with detection rates of 11.59%and 9.36%,respectively.Adenovirus was less common in autumn,with a detection rate of 5.39%.Conclusion:The application of nucleic acid detection of six common respiratory pathogens in the population of respiratory infection in Jinhu region can quickly diagnose the pathogen category,and provide a certain reference for the prevention and treatment of the disease in combination with the distribution characteristics of age,genders,season and epidemiological characteristics.关键词
呼吸道病原体/多重实时荧光定量PCR/呼吸道感染Key words
Respiratory pathogens/Multiple real-time fluorescent quantitative PCR/Respiratory tract infection引用本文复制引用
姜思源,唐彬..金湖地区呼吸道感染人群六种常见呼吸道病原体感染情况及分布特征[J].中国医学创新,2025,22(31):141-146,6.基金项目
淮安市科学技术局科技计划专项项目(HAB202352) （HAB202352）
