首页|期刊导航|针灸和草药（英文）|Integrated spatial metabolomics and transcriptomics reveal Ly6C+macrophage glutamine metabolism in pneumonia-mediated attenuation of aristolochic acid I nephrotoxicity

Integrated spatial metabolomics and transcriptomics reveal Ly6C+macrophage glutamine metabolism in pneumonia-mediated attenuation of aristolochic acid I nephrotoxicity

Chengxian Li Xiaohe Xiao Yinkang Wang Shuanglin Qin Xiaoyan Zhan Xu Zhao Mingxia Fang Jiaying Li Ming Niu Zhaofang Bai

针灸和草药（英文）2025，Vol.5Issue(3)：301-315,15.

针灸和草药（英文）2025，Vol.5Issue(3)：301-315,15.DOI:10.1097/HM9.0000000000000165

Integrated spatial metabolomics and transcriptomics reveal Ly6C+macrophage glutamine metabolism in pneumonia-mediated attenuation of aristolochic acid I nephrotoxicity

Chengxian Li ¹Xiaohe Xiao ²Yinkang Wang ³Shuanglin Qin ⁴Xiaoyan Zhan ²Xu Zhao ³Mingxia Fang ³Jiaying Li ⁵Ming Niu ⁶Zhaofang Bai²

作者信息

1. Institute of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,China||Haihe Laboratory of Modern Chinese Medicine,Tianjin,China
2. Department of Liver Disease,Fifth Medical Center of Chinese PLA General Hospital,Beijing,China||National Key Laboratory of Kidney Diseases,Beijing,China
3. Department of Liver Disease,Fifth Medical Center of Chinese PLA General Hospital,Beijing,China
4. National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology,Research Center for Precision Medication of Chinese Medicine,FuRong Laboratory,Hunan University of Chinese Medicine,Changsha,China
5. Department of Infectious Disease,Fifth Medical Center of Chinese PLA General Hospital,Beijing,China
6. Department of Hematology,the Fifth Medical Center of Chinese PLA General Hospital,Beijing,China
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摘要

关键词

Aristolochic acid I/Kidney damage/Oxidative stress/Spatial metabolomics/Xi Xin safety

Key words

Aristolochic acid I/Kidney damage/Oxidative stress/Spatial metabolomics/Xi Xin safety

引用本文复制引用

Chengxian Li,Xiaohe Xiao,Yinkang Wang,Shuanglin Qin,Xiaoyan Zhan,Xu Zhao,Mingxia Fang,Jiaying Li,Ming Niu,Zhaofang Bai..Integrated spatial metabolomics and transcriptomics reveal Ly6C+macrophage glutamine metabolism in pneumonia-mediated attenuation of aristolochic acid I nephrotoxicity[J].针灸和草药（英文）,2025,5(3):301-315,15.

基金项目

This study was supported by the Consulting Project Funds of the Chinese Academy of Engineering(2023-XZ-88,China),Key Program of the National Natural Science Foundation of China(81721002 and 82230118,China),and Key Program of the National Natural Science Foundation of China Regional Union Fund(U23A20519,China). （2023-XZ-88,China）

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