肿瘤防治研究2025，Vol.52Issue(11)：945-950,6.DOI:10.3971/j.issn.1000-8578.2025.25.0278
肺癌微创术后肋间神经阻滞镇痛和静脉自控镇痛泵在加速康复外科中的临床作用——一项前瞻性随机对照研究
Clinical Effects of Intercostal Nerve Block Analgesia and Patient Controlled Intravenous Analgesia in Enhanced Recovery After Minimally Invasive Surgery for Lung Cancer:A Prospective Randomized Controlled Trial
摘要
Abstract
Objective To compare the analgesic effects and adverse reactions between intercostal nerve block(ICNB)and patient controlled intravenous analgesia(PCIA).Methods From August 2022 to January 2023,180 patients with lung cancer who underwent thoracoscopic surgery were randomly divided into two groups:ICNB group(n=90)and PCIA group(n=90).The postoperative pain degree(VAS),location,nature;adverse events,such as nausea,vomiting,and dizziness;and other clinical symptoms were analyzed.Results The most common site of postoperative pain in both groups was surgical incision,and the nature of pain was distending pain.At 12 and 24 h after the operation,the pain degree in the ICNB group(1.10±0.91,3.12±1.29)was markedly lower than that in PCIA group(1.44±0.86,4.32±1.30,P=0.010,P<0.001).The incidence of nausea,vomiting,and dizziness in the ICNB group(5.56％,23.33％)was noticeably lower than that in the PCIA group(35.56％,51.11％,P<0.001,P<0.001).Total hospitalization expense in the ICNB group(41 043.16±10 885.63 yuan)was significantly lower than that in PCIA group(45283.99±11036.36 yuan,P=0.010).Conclusion The analgesic effect of intercostal nerve block is better than that of patient-controlled intravenous analgesia pump in patients with lung cancer after minimally invasive surgery,and the incidence of adverse reactions is low.关键词
肋间神经阻滞镇痛/静脉自控镇痛泵/加速康复外科/肺癌Key words
Intercostal nerve block analgesia/Patient controlled intravenous analgesia/Enhanced recovery after surgery/Lung cancer分类
临床医学引用本文复制引用
赵梓邑,叶云,陈曦,田龙,郑希,车国卫..肺癌微创术后肋间神经阻滞镇痛和静脉自控镇痛泵在加速康复外科中的临床作用——一项前瞻性随机对照研究[J].肿瘤防治研究,2025,52(11):945-950,6.基金项目
癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项(2023ZD0501706) （2023ZD0501706）
四川大学华西医院高原医学中心1·3·5工程基金(GYYX24008) （GYYX24008）
四川大学华西医院"1·3·5工程"人工智能项目(ZYAI24001) The Noncommunicable Chronic Diseases-National Science and Technology Major Project(No.2023ZD0501706) （ZYAI24001）
The 1·3·5 Project of Center for High Altitude Medicine,West China Hospital,Sichuan University(No.GYYX24008) （No.GYYX24008）
The 1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.ZYAI24001) （No.ZYAI24001）
