中医药信息2025，Vol.42Issue(11)：69-74,6.DOI:10.19656/j.cnki.1002-2406.20251111
白及多糖促糖尿病足溃疡创面愈合机制及其新型制剂研究进展
Research Progress of Bletilla striata Polysaccharide in Promoting Wound Healing of Diabetes Foot Ulcers and Novel Preparations
摘要
Abstract
As one of the most prevalent and serious complications of diabetes,diabetic foot ulcer is hard to treat clinically because of the complex pathogenesis which seriously affects patients'quality of life.Bletilla striata is an essential drug for astringent and hemostasis,and has the effect of detumescence and muscle regeneration,so often be used in clinical treatment of various chronic and refractory wounds.As the main effective ingredient of Bletilla striata,Bletilla striata polysaccharide(BSP)has multiple pharmacological effects such as hemostasis,antibacterial,antioxidant,anti-tumor and immune regulation.This article reviewed relevant literature to summarize that the study on BSP was in the treatment of gastrointestinal tract ulcer,antimicrobial and anti-inflammatory,anti-tumor,anti inflammatory and hemostasis,immune regulation and promotion of the healing of chronic wounds.In the treatment of diabetic foot ulcer,the BSP plays the role in the perspectives of antibacterial and anti-inflammatory,antioxidant,promotion of tissue regeneration and immune regulation.With the biocompatibility,biodegradability and non-toxicity,BSP is suitable to be used as drug delivery matrix,the preparation of hydrogels,dressings,microneedles and other traditional Chinese medicine preparations.关键词
白及多糖/糖尿病足溃疡/创面愈合/新型中药制剂/综述Key words
Bletilla striata polysaccharide/Diabetes foot ulcer/Wound healing/Novel traditional Chinese medicine preparations/Summary引用本文复制引用
吴沁怡,施吉群,强可儿,徐建达..白及多糖促糖尿病足溃疡创面愈合机制及其新型制剂研究进展[J].中医药信息,2025,42(11):69-74,6.基金项目
江苏省中医药管理局项目(20200053) （20200053）
