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Intratympanic dexamethasone microcrystals/lidocaine-loaded PLGA non-spherical microparticles for local drug delivery to the inner ear

Dongcheng Wang Xin Zhang Zhen Wang Cheng Ran Jia Hao Xiaobo Ma Minghui Wang Zhimin Zhou

Animal Models and Experimental Medicine2025，Vol.8Issue(10)：P.1813-1823,11.

Animal Models and Experimental Medicine2025，Vol.8Issue(10)：P.1813-1823,11.DOI:10.1002/ame2.70041

Intratympanic dexamethasone microcrystals/lidocaine-loaded PLGA non-spherical microparticles for local drug delivery to the inner ear

Dongcheng Wang ¹Xin Zhang ¹Zhen Wang ¹Cheng Ran ²Jia Hao ²Xiaobo Ma ³Minghui Wang ⁴Zhimin Zhou¹

作者信息

1. Biomedical Barriers Research Center,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin,China
2. Department of Otolaryngology,Affiliate Hospital of Hebei University,Baoding,China
3. Key Laboratory of Otolaryngology Head and Neck Surgery,Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Ministry of Education,Capital Medical University,Beijing,China
4. Department of Otorhinolaryngology Head and Neck Surgery,Tianjin Fourth Central Hospital,Tianjin,China
折叠

摘要

关键词

dexamethasone/inner ear delivery/lidocaine/microcrystals/non-spherical particles

分类

医药卫生

引用本文复制引用

Dongcheng Wang,Xin Zhang,Zhen Wang,Cheng Ran,Jia Hao,Xiaobo Ma,Minghui Wang,Zhimin Zhou..Intratympanic dexamethasone microcrystals/lidocaine-loaded PLGA non-spherical microparticles for local drug delivery to the inner ear[J].Animal Models and Experimental Medicine,2025,8(10):P.1813-1823,11.

基金项目

Tianjin Natural Science Foundation for Jingjinji Collaboration,Grant/Award Number:23JCZXJC00240 （）

Hebei Natural Science Foundation,Grant/Award Number:H2023201903 （）

Beijing Natural Science Foundation,Grant/Award Number:J230006 （）

Capital''s Funds for Health Improvement and Research,Grant/Award Number:CFH:2022-2-5072 （）

CAMS Innovation Fund for Medical Sciences,Grant/Award Number:2021-I2M-1-052。（）

Animal Models and Experimental Medicine

ISSN：2096-5451

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