Divergent roles of PKM2 in regulating PD-L1 and PD-L2 expression and their implications in human and mouse cancer models
Shuo He Shujuan Luo Bangwu Cai Jiao Chen Yao Zhang Feng Zhao Qing Liu Tao Liu Wei Wang Tianyuan Peng Xiaomei Lu Shutao Zheng
Divergent roles of PKM2 in regulating PD-L1 and PD-L2 expression and their implications in human and mouse cancer models
摘要
关键词
PKM2/PD-L1/PD-L2/GATA3/immune evasion分类
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Shuo He,Shujuan Luo,Bangwu Cai,Jiao Chen,Yao Zhang,Feng Zhao,Qing Liu,Tao Liu,Wei Wang,Tianyuan Peng,Xiaomei Lu,Shutao Zheng..Divergent roles of PKM2 in regulating PD-L1 and PD-L2 expression and their implications in human and mouse cancer models[J].Acta Biochimica et Biophysica Sinica,2025,57(10):P.1696-1708,13.基金项目
supported by the grants from the National Natural Science Foundation of China(Nos.82360521 and 82260568) (Nos.82360521 and 82260568)
the Xinjiang Science Fund for Distinguished Young Scholar(No.2022D01E26) (No.2022D01E26)
the Leading Talent Project of Scientific and Technological Innovation in Tianshan Talents Training Plan of Xinjiang Uygur Autonomous Region(No.2022TSYCLJ0031) (No.2022TSYCLJ0031)
the Major Research Project Incubation Program of Xinjiang Medical University(No.XYD2024ZX02) (No.XYD2024ZX02)
the Key Research and Development Project of the Xinjiang Uygur Autonomous Region(No.2020B03003) (No.2020B03003)
the State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia Fund(No.SKL-HIDCA-2024-15) (No.SKL-HIDCA-2024-15)
special funds for the development of local science and technology from the central government(No.ZYYD2022B06) (No.ZYYD2022B06)
the Innovative Team Training Project of the First Affiliated Hospital of Xinjiang Medical University(to X.L.). (to X.L.)